SCHEMBL21184380

SCHEMBL21184380

CO[C@@H]1[C@H](O)[C@@H](CO[PH](=O)O)O[C@H]1C

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ FBP1 P09467 1/20 0.33
▸ FGF1 P05230 1/20 0.30
▸ AMDHD2 Q9Y303 1/20 0.30
▸ LGALS8 O00214 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21184378 1.00 FBP1 (0.33) FBP1FGF1AMDHD2LGALS8
SCHEMBL21184288 0.83 FBP1 (0.40) FBP1AMDHD2
SCHEMBL21184290 0.83 FBP1 (0.40) FBP1AMDHD2
SCHEMBL15368857 0.83 FBP1 (0.40) FBP1AMDHD2
SCHEMBL19227509 0.79 OGA (0.34) FBP1FGF1LGALS8
SCHEMBL19760163 0.77 FBP1 (0.61) FBP1AMDHD2
SCHEMBL18755379 0.74 OGA (0.33) FGF1LGALS8
SCHEMBL15907822 0.74 OGA (0.36) FBP1FGF1
SCHEMBL12899675 0.73 LGALS8 (0.45) FGF1LGALS8
SCHEMBL15962117 0.73 LGALS8 (0.45) FGF1LGALS8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190225644-A1 MRNA CAP ANALOGS AND METHODS OF MRNA CAPPING MODERNATX, INC. 2019-07-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190225644-A1 MRNA CAP ANALOGS AND METHODS OF MRNA CAPPING RNGTT, RNMT, NSUN2 FBP1 2442/4885FGF1 4880/4885AMDHD2 959/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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