Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK7 | P50613 | 12/20 | 0.55 |
| ▸ | CCNH | P51946 | 12/20 | 0.55 |
| ▸ | MNAT1 | P51948 | 12/20 | 0.55 |
| ▸ | CCNK | O75909 | 12/20 | 0.55 |
| ▸ | CDK12 | Q9NYV4 | 12/20 | 0.55 |
| ▸ | CCNT1 | O60563 | 11/20 | 0.55 |
| ▸ | CDK9 | P50750 | 11/20 | 0.55 |
| ▸ | CCNE1 | P24864 | 9/20 | 0.55 |
| ▸ | CDK2 | P24941 | 9/20 | 0.55 |
| ▸ | ULK1 | O75385 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21184588 | 0.82 | CCNK (0.46) | CDK7CCNHMNAT1CCNKCDK12 | |
| SCHEMBL21184300 | 0.77 | CCNK (0.59) | CDK7CCNHMNAT1CCNKCDK12 | |
| SCHEMBL21184555 | 0.77 | CCNK (0.59) | CDK7CCNHMNAT1CCNKCDK12 | |
| SCHEMBL24839616 | 0.71 | CCNK (1.00) | CDK7CCNHMNAT1CCNKCDK12 | |
| SCHEMBL21184570 | 0.70 | CDK7 (0.34) | CDK7CCNHMNAT1CCNKCDK12 | |
| SCHEMBL21184593 | 0.67 | CDK7 (0.53) | CDK7CCNHMNAT1CCNKCDK12 | |
| SCHEMBL21184490 | 0.66 | ULK1 (0.63) | CDK7CCNHMNAT1CCNKCDK12 | |
| SCHEMBL25529565 | 0.64 | CCNE1 (0.58) | CDK7CCNHMNAT1CCNKCDK12 | |
| SCHEMBL21184589 | 0.64 | CCNK (0.64) | CDK7CCNHMNAT1CCNKCDK12 | |
| SCHEMBL21184407 | 0.64 | RORC (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019143730-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) | SYROS PHARMACEUTICALS, INC. (US) | 2019-07-25 | — | — | WO | disclosed |