Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | USP8 | P40818 | 1/20 | 0.42 |
| ▸ | PRF1 | P14222 | 3/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | GHSR | Q92847 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2119515 | 0.89 | CCR9 (0.40) | MAPTALDH1A1CYP2C9TSHRNPSR1 | |
| SCHEMBL2118227 | 0.85 | GHSR (0.47) | MAPTALDH1A1CYP2C9TSHRNPSR1 | |
| SCHEMBL2119624 | 0.81 | SLC40A1 (0.47) | MAPTALDH1A1PRF1HSD17B1HSD17B2 | |
| SCHEMBL2117419 | 0.80 | USP2 (0.42) | MAPTALDH1A1CYP2C9TSHRNPSR1 | |
| SCHEMBL2116804 | 0.80 | KIT (0.46) | MAPTALDH1A1CYP2C9TSHRNPSR1 | |
| SCHEMBL2117810 | 0.80 | HSD17B1 (0.47) | MAPTALDH1A1CYP2C9HSD17B1HSD17B2 | |
| SCHEMBL2119972 | 0.80 | MAPT (0.42) | MAPTALDH1A1CYP2C9TSHRNPSR1 | |
| SCHEMBL2121581 | 0.79 | TRIM24 (0.49) | MAPTALDH1A1CYP2C9TSHRNPSR1 | |
| SCHEMBL2119304 | 0.78 | ALDH1A1 (0.43) | MAPTALDH1A1CYP2C9TSHRNPSR1 | |
| SCHEMBL2120887 | 0.78 | ALDH1A1 (0.40) | MAPTALDH1A1CYP2C9TSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120095012-A1 | TOLUIDINE SULFONAMIDES AND THEIR USE | ELARA PHARMACEUTICALS GMBH (DE) | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095012-A1 | TOLUIDINE SULFONAMIDES AND THEIR USE | HIF1A, HIF1AN, EGLN3 | MAPT 4747/4885ALDH1A1 1063/4885CYP2C9 2049/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.