Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 8/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 7/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21186226 | 0.86 | NCOA1 (0.43) | SLC6A4SLC6A2SLC6A3HTR2AKCNH2 | |
| SCHEMBL4687458 | 0.81 | HSD11B1 (0.45) | MAPTLMNAHTTHSD11B1GAA | |
| SCHEMBL11018978 | 0.80 | ALDH1A1 (0.50) | SLC6A4SLC6A2SLC6A3HTR2AKCNH2 | |
| SCHEMBL21186227 | 0.78 | PLA2G7 (0.49) | SLC6A4SLC6A2SLC6A3MAPTHSD11B1 | |
| SCHEMBL21186204 | 0.76 | ALDH1A1 (0.51) | SLC6A4SLC6A2SLC6A3HTR2AKCNH2 | |
| SCHEMBL21186237 | 0.75 | ALDH1A1 (0.39) | SLC6A4SLC6A2SLC6A3MAPTLMNA | |
| SCHEMBL31264488 | 0.75 | PDE7A (0.56) | SLC6A4SLC6A2SLC6A3HTR2AKCNH2 | |
| SCHEMBL3045884 | 0.75 | SLC6A2 (0.55) | SLC6A4SLC6A2SLC6A3MAPTGAA | |
| SCHEMBL21186209 | 0.75 | PDE7A (0.56) | SLC6A4SLC6A2SLC6A3HTR2AKCNH2 | |
| SCHEMBL15955628 | 0.71 | SLC6A4 (0.44) | SLC6A4SLC6A2SLC6A3HTR2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019141980-A1 | AGRICULTURAL CHEMICALS | GLOBACHEM NV (BE) | 2019-07-25 | — | — | WO | disclosed |