Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.46 |
| ▸ | FES | P07332 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | GSK3A | P49840 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.46 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.46 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.46 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.46 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.46 |
| ▸ | CSNK1G3 | Q9Y6M4 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21186172 | 0.90 | NPC1 (0.55) | NPC1RAB9ACHRM4KMT2AKDM4E | |
| SCHEMBL21186164 | 0.89 | RORC (0.46) | NPC1RAB9ADCLK1FESPIM1 | |
| SCHEMBL21186013 | 0.84 | RIPK1 (0.44) | NPC1RAB9ACHRM4KMT2AKDM4E | |
| SCHEMBL21186170 | 0.82 | NPC1 (0.51) | NPC1RAB9ACHRM4KMT2AKDM4E | |
| SCHEMBL21186000 | 0.80 | KMT2A (0.42) | NPC1RAB9ACHRM4KMT2AKDM4E | |
| SCHEMBL21186146 | 0.78 | NPC1 (0.61) | NPC1RAB9ADCLK1FESPIM1 | |
| SCHEMBL21186168 | 0.78 | DCLK1 (0.53) | NPC1RAB9ADCLK1FESPIM1 | |
| SCHEMBL21186121 | 0.78 | NPC1 (0.43) | NPC1RAB9ACHRM4KMT2AKDM4E | |
| SCHEMBL21186175 | 0.77 | DCLK1 (0.56) | NPC1RAB9ADCLK1FESPIM1 | |
| SCHEMBL21186165 | 0.76 | NPC1 (0.64) | NPC1RAB9ADCLK1FESPIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019141980-A1 | AGRICULTURAL CHEMICALS | GLOBACHEM NV (BE) | 2019-07-25 | — | — | WO | disclosed |