Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | RORC | P51449 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.43 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21186164 | 0.91 | RORC (0.46) | NPC1RAB9ARORCALDH1A1MAPT | |
| SCHEMBL21186166 | 0.90 | NPC1 (0.57) | NPC1RAB9ARORCALDH1A1MAPT | |
| SCHEMBL21186013 | 0.86 | RIPK1 (0.44) | NPC1RAB9ARORCALDH1A1MAPT | |
| SCHEMBL21186170 | 0.84 | NPC1 (0.51) | NPC1RAB9AALDH1A1MAPTKDM4E | |
| SCHEMBL21186000 | 0.82 | KMT2A (0.42) | NPC1RAB9AALDH1A1MAPTKDM4E | |
| SCHEMBL21186199 | 0.81 | NPC1 (0.59) | NPC1RAB9ARORCALDH1A1MAPT | |
| SCHEMBL21186146 | 0.80 | NPC1 (0.61) | NPC1RAB9AALDH1A1MAPTKDM4E | |
| SCHEMBL21186121 | 0.80 | NPC1 (0.43) | NPC1RAB9AALDH1A1KDM4EKMT2A | |
| SCHEMBL4909146 | 0.79 | NPC1 (0.65) | NPC1RAB9ARORCALDH1A1MAPT | |
| SCHEMBL21186165 | 0.78 | NPC1 (0.64) | NPC1RAB9AALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019141980-A1 | AGRICULTURAL CHEMICALS | GLOBACHEM NV (BE) | 2019-07-25 | — | — | WO | disclosed |