SCHEMBL21186367

SCHEMBL21186367

C/C=C\C=C(/C)P(=O)(c1ccccc1)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
CA2 P00918 1/20 0.39
CA4 P22748 1/20 0.39
CA5A P35218 1/20 0.39
TSHR P16473 3/20 0.37
ALOX15 P16050 2/20 0.37
ESR1 P03372 1/20 0.37
GAA P10253 3/20 0.36
LMNA P02545 2/20 0.36
USP2 O75604 2/20 0.36
CFTR P13569 1/20 0.35
ALDH1A1 P00352 4/20 0.33
MEN1 O00255 2/20 0.33
PKM P14618 1/20 0.33
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21741328 0.91 KMT2A (0.37) KMT2AL3MBTL1CA2CA4CA5A
SCHEMBL21973180 0.79 ALDH1A1 (0.43) KMT2AL3MBTL1ALDH1A1MEN1POLB
SCHEMBL22100873 0.78 GPR84 (0.33) L3MBTL1TSHRALDH1A1
SCHEMBL22335663 0.77 TSHR (0.42) KMT2AL3MBTL1CA2CA4CA5A
SCHEMBL23369444 0.73 DRD1 (0.36) KMT2AMEN1
SCHEMBL24975959 0.73 KMT2A (0.39) KMT2AL3MBTL1CA2CA4CA5A
SCHEMBL19778561 0.69 KMT2A (0.42) KMT2AL3MBTL1CA2CA4CA5A
SCHEMBL22229050 0.69 KMT2A (0.42) KMT2AL3MBTL1CA2CA4CA5A
SCHEMBL19778904 0.69 TSHR (0.44) KMT2AL3MBTL1CA2CA4CA5A
SCHEMBL8847094 0.69 KMT2A (0.53) KMT2AL3MBTL1CA2CA4CA5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021256633-A1 ECO-FRIENDLY HEAT-SHIELDING COMPOSITE TUNGSTEN COMPOSITION AND METHOD FOR PREPARING SAME 황태경 2021-12-23 WO disclosed
US-20190227047-A1 CONDITION DIAGNOSIS AND A LIFE-EXTENDING TREATMENT METHOD FOR AN ELECTRIC APPARATUS CONTAINING INSULATION OIL AND ITS ASSOCIATED SYSTEM VP DIAGNOSE AS (NO) 2019-07-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190227047-A1 CONDITION DIAGNOSIS AND A LIFE-EXTENDING TREATMENT METHOD FOR AN ELECTRIC APPARATUS CONTAINING INSULATION OIL AND ITS ASSOCIATED SYSTEM GSS, TST, SELENOI KMT2A 3593/4885L3MBTL1 2167/4885CA2 2145/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.