Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.43 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24433157 | 0.88 | CA2 (0.38) | TDP1PTGS2ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL21186462 | 0.86 | PSIP1 (0.46) | TDP1PSIP1PCSK9PTGS2SMN1; SMN2 | |
| SCHEMBL21712439 | 0.79 | TDP1 (0.47) | TDP1PSIP1PCSK9PTGS2ALDH1A1 | |
| SCHEMBL2839087 | 0.79 | TDP1 (0.47) | TDP1PSIP1PCSK9PTGS2ALDH1A1 | |
| SCHEMBL22041066 | 0.77 | SIGMAR1 (0.44) | TDP1PSIP1LTA4H | |
| SCHEMBL22041446 | 0.77 | HTR2A (0.46) | TDP1 | |
| SCHEMBL21191483 | 0.76 | TDP1 (0.44) | TDP1PSIP1PCSK9PTGS2ALDH1A1 | |
| SCHEMBL777886 | 0.76 | PSIP1 (0.64) | TDP1PSIP1ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL19561677 | 0.75 | PSIP1 (0.56) | TDP1PSIP1PTGS2ALDH1A1TSHR | |
| SCHEMBL22916153 | 0.74 | GAA (0.40) | TDP1ALDH1A1TSHRABCB1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190225629-A1 | METHOD FOR PREPARING SILAHYDROCARBONS | UNIVERSITY OF DELAWARE (US) | 2019-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190225629-A1 | METHOD FOR PREPARING SILAHYDROCARBONS | MCM6, CCNY, RIOX2 | TDP1 3660/4885PSIP1 3560/4885PCSK9 3822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.