Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | FPR2 | P25090 | 3/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | FPR1 | P21462 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21187199 | 0.88 | FPR1 (0.47) | KMT2AFPR2EPHX2NPC1RAB9A | |
| SCHEMBL21187119 | 0.88 | NPC1 (0.51) | KMT2AEPHX2NPC1RAB9AEPHX1 | |
| SCHEMBL21187195 | 0.88 | NPC1 (0.51) | KMT2AEPHX2NPC1RAB9AEPHX1 | |
| SCHEMBL21187129 | 0.84 | RAB9A (0.49) | NPC1RAB9AMAPTALDH1A1CYP1A2 | |
| SCHEMBL21187148 | 0.82 | MAOA (0.45) | MAOAMAOBKMT2AFPR2EPHX2 | |
| SCHEMBL21187149 | 0.81 | NPC1 (0.46) | KMT2AEPHX2NPC1RAB9AEPHX1 | |
| SCHEMBL21187147 | 0.81 | EPHX1 (0.45) | FPR2EPHX2NPC1RAB9AEPHX1 | |
| SCHEMBL20852665 | 0.76 | KLK7 (0.53) | MAOAMAOBFPR2NPC1RAB9A | |
| SCHEMBL20838632 | 0.76 | KLK7 (0.53) | MAOAMAOBFPR2NPC1RAB9A | |
| SCHEMBL17737340 | 0.76 | KLK7 (0.53) | MAOAMAOBFPR2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019141095-A1 | AMIDINE AND GUANIDINE DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2019-07-25 | — | — | WO | disclosed |