Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK7 | P50613 | 3/20 | 0.32 |
| ▸ | CCNH | P51946 | 3/20 | 0.32 |
| ▸ | MNAT1 | P51948 | 3/20 | 0.32 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21188482 | 0.71 | PDPK1 (0.37) | PDPK1 | |
| SCHEMBL27428231 | 0.63 | NUDT1 (0.35) | CDK7CCNHMNAT1 | |
| SCHEMBL19461895 | 0.60 | TLR8 (0.43) | — | |
| SCHEMBL21188782 | 0.58 | CLK1 (0.43) | CDK7CCNHMNAT1 | |
| Water SCHEMBL28123349 | 0.55 | TYR (0.33) | — | |
| SCHEMBL29848848 | 0.54 | BRD4 (0.47) | — | |
| SCHEMBL16651985 | 0.54 | BRD4 (0.47) | — | |
| SCHEMBL25043383 | 0.52 | MEN1 (0.40) | — | |
| SCHEMBL12627364 | 0.52 | JAK2 (0.65) | CDK7CCNHMNAT1 | |
| SCHEMBL22994824 | 0.52 | NR4A2 (0.53) | CDK7CCNHMNAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019143719-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) | SYROS PHARMACEUTICALS, INC. (US) | 2019-07-25 | — | — | WO | disclosed |