SCHEMBL21189658

SCHEMBL21189658

CC(c1ccc(-c2ccccc2)cc1)(c1ccc(S)cc1S)c1ccc(S)cc1S

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 2/20 0.41
CYP2C9 P11712 1/20 0.37
ESR1 P03372 2/20 0.35
ESR2 Q92731 2/20 0.35
AKT1 P31749 1/20 0.32
AKT2 P31751 1/20 0.32
PTPN5 P54829 1/20 0.32
RXRA P19793 1/20 0.31
RXRB P28702 1/20 0.31
BACE1 P56817 2/20 0.31
GLO1 Q04760 1/20 0.31
DGAT1 O75907 1/20 0.31
KCNH2 Q12809 1/20 0.31
HSD17B2 P37059 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21189657 0.90 ESR1 (0.39) ESR1ESR2ALDH1A1
SCHEMBL21189663 0.88 ESR1 (0.30) ESR1ESR2
SCHEMBL22737749 0.85 KIF11 (0.40) KIF11CYP2C9ESR1ESR2PTPN5
SCHEMBL22991391 0.83
SCHEMBL21189660 0.82 KIF11 (0.47) KIF11CYP2C9ESR1ESR2AKT1
SCHEMBL21189631 0.82 KIF11 (0.40) KIF11CYP2C9ESR1ESR2AKT1
SCHEMBL21189659 0.80 ESR1 (0.48) KIF11CYP2C9ESR1ESR2AKT1
SCHEMBL22738142 0.79 PDE2A (0.35) ESR1ESR2
SCHEMBL22991378 0.79 KIF11 (0.31) KIF11
SCHEMBL21189809 0.77 ESR1 (0.35) KIF11CYP2C9ESR1ESR2RXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019142897-A1 COMPOUND, RESIN, COMPOSITION, AND PATTERN FORMING METHOD 三菱瓦斯化学株式会社 2019-07-25 WO disclosed