SCHEMBL21189659

SCHEMBL21189659

CC(c1ccc(S)cc1)(c1ccc(S)cc1)c1ccc(-c2ccccc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.48
ESR2 Q92731 3/20 0.48
KIF11 P52732 2/20 0.46
CYP2C9 P11712 1/20 0.41
ALDH1A1 P00352 3/20 0.39
PTPN5 P54829 1/20 0.38
AKT1 P31749 1/20 0.38
AKT2 P31751 1/20 0.38
CYP3A4 P08684 2/20 0.36
MAPK1 P28482 1/20 0.36
CYP1A2 P05177 1/20 0.36
TAAR1 Q96RJ0 1/20 0.36
HSD17B10 Q99714 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
MMP3 P08254 1/20 0.36
BCL2L1 Q07817 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22737750 0.92 ESR1 (0.42) ESR1ESR2KIF11CYP2C9ALDH1A1
SCHEMBL21189655 0.89 ESR1 (0.60) ESR1ESR2ALDH1A1CYP3A4MAPK1
SCHEMBL21189662 0.83 ESR1 (0.44) ESR1ESR2CYP3A4HSD17B10
SCHEMBL21189631 0.82 KIF11 (0.40) ESR1ESR2KIF11CYP2C9PTPN5
SCHEMBL94499 0.81 ALDH1A1 (0.60) KIF11ALDH1A1CYP3A4MAPK1CYP1A2
SCHEMBL966905 0.81 ALDH1A1 (0.60) KIF11ALDH1A1CYP3A4MAPK1CYP1A2
Biphenyl SCHEMBL28041385 0.81 ALDH1A1 (0.60) KIF11ALDH1A1CYP3A4MAPK1CYP1A2
SCHEMBL12696283 0.81 ALDH1A1 (0.60) KIF11ALDH1A1CYP3A4MAPK1CYP1A2
SCHEMBL21189658 0.80 KIF11 (0.41) ESR1ESR2KIF11CYP2C9ALDH1A1
SCHEMBL22991636 0.79 ESR1 (0.44) ESR1ESR2KIF11ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019142897-A1 COMPOUND, RESIN, COMPOSITION, AND PATTERN FORMING METHOD 三菱瓦斯化学株式会社 2019-07-25 WO disclosed