SCHEMBL21189678

SCHEMBL21189678

CC(c1ccc2ccccc2c1)(c1cc(-c2ccc(S)cc2)ccc1S)c1cc(-c2ccc(S)cc2)ccc1S

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.37
ESR2 Q92731 1/20 0.37
CHRNB2 P17787 1/20 0.33
CHRNB4 P30926 1/20 0.33
CHRNA3 P32297 1/20 0.33
CHRNA7 P36544 1/20 0.33
CHRNA4 P43681 1/20 0.33
LPL P06858 1/20 0.33
LIPG Q9Y5X9 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
PTPN1 P18031 1/20 0.33
ALOX5 P09917 1/20 0.33
CASR P41180 1/20 0.32
CYP11B1 P15538 2/20 0.32
CYP11B2 P19099 2/20 0.32
HSD17B1 P14061 1/20 0.32
HSD17B2 P37059 1/20 0.32
CYP1A2 P05177 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22737841 0.94 ESR1 (0.33) ESR1ESR2HSD11B1
SCHEMBL21189631 0.85 KIF11 (0.40) ESR1ESR2PTPN1ALOX5HSD17B2
SCHEMBL21189637 0.85 KIF11 (0.31)
SCHEMBL21189812 0.85 KIF11 (0.31)
SCHEMBL21189809 0.83 ESR1 (0.35) ESR1ESR2PTPN1
SCHEMBL21189821 0.79 ALDH1A1 (0.30)
SCHEMBL22738049 0.78
SCHEMBL23861504 0.77 ESR1 (0.56) ESR1ESR2ALOX5HSD17B1HSD17B2
SCHEMBL22991378 0.76 KIF11 (0.31)
SCHEMBL22737576 0.74 AR (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019142897-A1 COMPOUND, RESIN, COMPOSITION, AND PATTERN FORMING METHOD 三菱瓦斯化学株式会社 2019-07-25 WO disclosed