Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 6/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 6/20 | 0.36 |
| ▸ | BRD4 | O60885 | 3/20 | 0.34 |
| ▸ | CA1 | P00915 | 5/20 | 0.33 |
| ▸ | CA2 | P00918 | 5/20 | 0.33 |
| ▸ | CA9 | Q16790 | 5/20 | 0.33 |
| ▸ | CA5A | P35218 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.33 |
| ▸ | F11 | P03951 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6240959 | 0.87 | CA1 (0.44) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL20157282 | 0.87 | LIPG (0.37) | LPLLIPGBRD4CA1CA2 | |
| SCHEMBL24456291 | 0.82 | KMT2A (0.39) | LPLLIPGBRD4CA1CA2 | |
| SCHEMBL9937303 | 0.81 | LPL (0.36) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL2522891 | 0.81 | LPL (0.36) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL16658429 | 0.80 | BRD4 (0.38) | LPLLIPGBRD4CA1CA2 | |
| SCHEMBL15000455 | 0.78 | LIPG (0.40) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL21190845 | 0.78 | BRD4 (0.43) | BRD4CA1CA2CA9 | |
| SCHEMBL20157690 | 0.78 | SRD5A2 (0.37) | BRD4CA1CA2CA9UCHL1 | |
| SCHEMBL2947811 | 0.77 | G6PD (0.37) | CA1CA2CA9CA5ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019141131-A1 | BROMODOMAIN INHIBITOR COMPOUND AND USE THEREOF | 中国科学院上海药物研究所 | 2019-07-25 | — | — | WO | disclosed |