Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 10/20 | 0.44 |
| ▸ | CA2 | P00918 | 10/20 | 0.44 |
| ▸ | CA9 | Q16790 | 10/20 | 0.44 |
| ▸ | CA5A | P35218 | 4/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | LPL | P06858 | 6/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 6/20 | 0.36 |
| ▸ | F11 | P03951 | 1/20 | 0.35 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21190846 | 0.87 | LPL (0.36) | CA1CA2CA9CA5ACA12 | |
| SCHEMBL24456291 | 0.78 | KMT2A (0.39) | CA1CA2CA9CA5ACA12 | |
| SCHEMBL30774095 | 0.78 | CA1 (0.46) | CA1CA2CA9CA5ACA12 | |
| SCHEMBL2950528 | 0.78 | CA1 (0.46) | CA1CA2CA9CA5ACA12 | |
| SCHEMBL790052 | 0.77 | CA1 (0.58) | CA1CA2CA9CA5ACA12 | |
| SCHEMBL15000455 | 0.77 | LIPG (0.40) | CA1CA2CA9LPLLIPG | |
| SCHEMBL20157282 | 0.77 | LIPG (0.37) | CA1CA2CA9CA5ACA12 | |
| SCHEMBL1118853 | 0.75 | LIPG (0.56) | CA1CA2CA9CA5ACA12 | |
| SCHEMBL15181139 | 0.75 | UCHL1 (0.37) | CA1CA2CA9LPLLIPG | |
| SCHEMBL27875445 | 0.75 | SLC22A12 (0.44) | CA2LPLLIPGUCHL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1519915-A2 | TRICYCLIC STEROID HORMONE NUCLEAR RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-04-06 | — | — | EP | disclosed |
| WO-2004052847-A2 | TRICYCLIC STEROID HORMONE NUCLEAR RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2004-06-24 | — | — | WO | disclosed |