Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 11/20 | 0.46 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21190859 | 0.87 | TTR (0.50) | NR3C1EPAS1PTGER4PTGER2PKM | |
| SCHEMBL21191129 | 0.83 | KDM4E (0.45) | NR3C1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL21191013 | 0.83 | TTR (0.53) | NR3C1SLC6A2SLC6A4 | |
| SCHEMBL27689753 | 0.82 | PKM (0.47) | EPAS1SLC6A2SLC6A4SLC6A3HSPB1 | |
| SCHEMBL30444289 | 0.82 | EPAS1 (0.52) | NR3C1EPAS1HSPB1PKM | |
| SCHEMBL15067971 | 0.82 | EPAS1 (0.52) | NR3C1EPAS1HSPB1PKM | |
| SCHEMBL21190858 | 0.81 | SLC6A4 (0.41) | NR3C1EPAS1PTGER4PTGER2SLC6A2 | |
| SCHEMBL8695511 | 0.81 | SLC6A4 (0.40) | NR3C1PTGER4PTGER2SLC6A2SLC6A4 | |
| SCHEMBL21190854 | 0.79 | BRD4 (0.50) | NR3C1EPAS1SLC6A4 | |
| SCHEMBL12239036 | 0.79 | ST14 (0.50) | NR3C1SLC6A4PKMMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019141131-A1 | BROMODOMAIN INHIBITOR COMPOUND AND USE THEREOF | 中国科学院上海药物研究所 | 2019-07-25 | — | — | WO | disclosed |
| US-9359548-B2 | Organic electroluminescent device | UDC IRELAND LIMITED (IE) | 2016-06-07 | — | — | US | disclosed |