Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.50 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 7/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21190850 | 0.87 | NR3C1 (0.46) | EPAS1NR3C1PTGER4PTGER2PKM | |
| SCHEMBL14656214 | 0.85 | TTR (0.51) | TTRNR3C1LTA4HPTGER4PTGER2 | |
| SCHEMBL21191130 | 0.83 | TTR (0.53) | TTREPAS1NR3C1LTA4HMEN1 | |
| SCHEMBL21191014 | 0.83 | TTR (0.72) | TTRNR3C1LTA4H | |
| SCHEMBL27689753 | 0.82 | PKM (0.47) | EPAS1PKM | |
| SCHEMBL15068243 | 0.82 | EPAS1 (0.52) | TTREPAS1NR3C1PKMMEN1 | |
| SCHEMBL21190858 | 0.81 | SLC6A4 (0.41) | EPAS1NR3C1PTGER4PTGER2CARM1 | |
| SCHEMBL10889454 | 0.81 | CYP4F2 (0.53) | TTRLTA4HPTGER4PTGER2NPC1 | |
| SCHEMBL21190854 | 0.79 | BRD4 (0.50) | EPAS1NR3C1 | |
| SCHEMBL12239036 | 0.79 | ST14 (0.50) | NR3C1PKMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019141131-A1 | BROMODOMAIN INHIBITOR COMPOUND AND USE THEREOF | 中国科学院上海药物研究所 | 2019-07-25 | — | — | WO | disclosed |
| US-9359548-B2 | Organic electroluminescent device | UDC IRELAND LIMITED (IE) | 2016-06-07 | — | — | US | disclosed |