Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 7/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21191132 | 0.85 | SLC6A4 (0.42) | SLC6A4SLC6A2SLC6A3NR3C1HTR2A | |
| SCHEMBL15068139 | 0.84 | EPAS1 (0.48) | NR3C1HTR2ACARM1PRMT6MEN1 | |
| SCHEMBL21190859 | 0.81 | TTR (0.50) | NR3C1PTGER4PTGER2CARM1PRMT6 | |
| SCHEMBL21190850 | 0.81 | NR3C1 (0.46) | SLC6A4SLC6A2SLC6A3NR3C1PTGER4 | |
| SCHEMBL21190854 | 0.77 | BRD4 (0.50) | SLC6A4NR3C1EPAS1 | |
| SCHEMBL27689753 | 0.77 | PKM (0.47) | SLC6A4SLC6A2SLC6A3HTR2ALMNA | |
| SCHEMBL8298052 | 0.74 | SLC6A4 (0.48) | SLC6A4SLC6A2SLC6A3NR3C1HTR2A | |
| SCHEMBL12239036 | 0.74 | ST14 (0.50) | SLC6A4NR3C1HTR2AMEN1MAPT | |
| SCHEMBL16658441 | 0.73 | MAPT (0.45) | LMNAMEN1MAPTKMT2A | |
| SCHEMBL30812070 | 0.72 | MAOB (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019141131-A1 | BROMODOMAIN INHIBITOR COMPOUND AND USE THEREOF | 中国科学院上海药物研究所 | 2019-07-25 | — | — | WO | disclosed |
| US-9359548-B2 | Organic electroluminescent device | UDC IRELAND LIMITED (IE) | 2016-06-07 | — | — | US | disclosed |