Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | NPY1R | P25929 | 1/20 | 0.40 |
| ▸ | NPY2R | P49146 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.40 |
| ▸ | PDE4A | P27815 | 4/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3723725 | 0.98 | CSNK2A1 (0.41) | THRATHRBKMT2AMEN1NPY1R | |
| SCHEMBL21190896 | 0.80 | THRA (0.49) | THRATHRBKMT2AMEN1NPY1R | |
| SCHEMBL20384189 | 0.79 | HPGD (0.43) | KMT2AMEN1NPY1RNPY2RCSNK2A1 | |
| SCHEMBL20384187 | 0.79 | CSNK2A1 (0.43) | THRATHRBKMT2AMEN1NPY1R | |
| SCHEMBL20384188 | 0.79 | KMT2A (0.40) | THRATHRBKMT2AMEN1NPY1R | |
| SCHEMBL3724558 | 0.79 | CSNK2A1 (0.58) | CSNK2A1PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL12355729 | 0.79 | KMT2A (0.50) | THRATHRBKMT2AMEN1NPY1R | |
| SCHEMBL20021966 | 0.77 | CSNK2A1 (0.44) | KMT2AMEN1NPY1RNPY2RCSNK2A1 | |
| SCHEMBL3724488 | 0.77 | CSNK2A1 (0.59) | CSNK2A1PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL16335376 | 0.77 | PKM (0.42) | KMT2AMEN1NPY1RNPY2RCSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |