SCHEMBL21202085

SCHEMBL21202085

C=C1C[C@@]23CC[C@@H]4[C@](C)(CO[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)[C@H]5O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)CCC[C@@]4(C)[C@@H]2CC[C@@H]1C3

nearest known ligand 0.55

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ HSD11B1 P28845 3/20 0.55
▸ HSD11B2 P80365 1/20 0.55
▸ SELP P16109 1/20 0.45
▸ PTPN1 P18031 1/20 0.44
▸ ACHE P22303 2/20 0.38
▸ BCHE P06276 1/20 0.38
▸ XDH P47989 2/20 0.38
▸ SYNJ2 O15056 1/20 0.35
▸ F3 P13726 3/20 0.34
▸ TOP1 P11387 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19755907 0.97 HSD11B1 (0.51) HSD11B1HSD11B2SELPPTPN1ACHE
SCHEMBL26711280 0.96 HSD11B1 (0.51) HSD11B1HSD11B2SELPPTPN1ACHE
SCHEMBL24961911 0.92 HSD11B1 (0.46) HSD11B1HSD11B2SELPPTPN1ACHE
SCHEMBL17982560 0.85 PTPN1 (0.53) HSD11B1HSD11B2SELPPTPN1F3
SCHEMBL21202083 0.85 PTPN1 (0.53) HSD11B1HSD11B2SELPPTPN1F3
SCHEMBL16048075 0.85 PTPN1 (0.53) HSD11B1HSD11B2SELPPTPN1F3
SCHEMBL18979864 0.85 PTPN1 (0.53) HSD11B1HSD11B2SELPPTPN1F3
SCHEMBL23541386 0.83 SYNJ2 (0.41) HSD11B1HSD11B2SELPACHEXDH
SCHEMBL19755906 0.83 PTPN1 (0.50) HSD11B1HSD11B2SELPPTPN1F3
SCHEMBL24961200 0.82 SELP (0.49) HSD11B1HSD11B2SELPPTPN1F3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10364450-B2 Production of steviol glycoside in recombinant hosts EVOLVA SA (CH) 2019-07-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10364450-B2 Production of steviol glycoside in recombinant hosts ERG28, KISS1R, STT3A HSD11B1 160/4885HSD11B2 149/4885SELP 1162/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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