Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 4/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.35 |
| ▸ | HTR3B | O95264 | 3/20 | 0.35 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.35 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21208473 | 0.88 | GRM2 (0.39) | CYP11B1CYP11B2GRM2ATMHTR3A | |
| SCHEMBL21208469 | 0.85 | CYP11B1 (0.37) | CYP11B1CYP11B2GRM2ATMHTR3A | |
| SCHEMBL21208471 | 0.82 | HRH4 (0.45) | CYP11B1CYP11B2HTR3AKDM4EPKM | |
| SCHEMBL21217322 | 0.80 | TNKS (0.33) | ATMKDM4EPARP1RAB9A | |
| SCHEMBL21208485 | 0.79 | HTR3A (0.41) | CYP11B1CYP11B2HTR3AHTR3EHTR3B | |
| SCHEMBL21208513 | 0.78 | HTR3E (0.40) | GRM2HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL19636345 | 0.78 | KDM4E (0.40) | CYP11B1CYP11B2ATMHTR3AHTR3E | |
| SCHEMBL19636346 | 0.77 | PARP1 (0.38) | CYP11B1CYP11B2HTR3AHTR3EHTR3B | |
| SCHEMBL21208484 | 0.77 | HRH4 (0.36) | CYP11B1CYP11B2HTR3AHTR3EHTR3B | |
| SCHEMBL21208486 | 0.76 | EHMT1 (0.41) | CYP11B1CYP11B2HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317120-A1 | NOVEL COMPOSITIONS, USES AND METHODS FOR MAKING THEM | UNITED STATES GOVERNMENT | 2021-10-14 | — | — | US | disclosed |
| US-10975076-B2 | Compositions, uses and methods for making them | Pimera, Inc. (US) | 2021-04-13 | — | — | US | disclosed |
| US-20190233422-A1 | NOVEL COMPOSITIONS, USES AND METHODS FOR MAKING THEM | UNITED STATES GOVERNMENT | 2019-08-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10975076-B2 | Compositions, uses and methods for making them | BAX, CASP3, CASP7 | CYP11B1 49/4885CYP11B2 82/4885GRM2 4756/4885 |
| US-20190233422-A1 | NOVEL COMPOSITIONS, USES AND METHODS FOR MAKING THEM | BAX, CASP3, BCL2 | CYP11B1 99/4885CYP11B2 144/4885GRM2 4592/4885 |
| US-20210317120-A1 | NOVEL COMPOSITIONS, USES AND METHODS FOR MAKING THEM | BAX, CASP3, CASP7 | CYP11B1 76/4885CYP11B2 157/4885GRM2 4611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.