Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PI4KA | P42356 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20169567 | 0.82 | KAT6A (0.35) | KDM4EMAPTLMNASMN1; SMN2TP53 | |
| SCHEMBL21215771 | 0.78 | NPC1 (0.44) | SIRT2KDM4EMAPTLMNAPKM | |
| SCHEMBL21215633 | 0.78 | KDM4E (0.50) | SIRT2KDM4EMAPTLMNAPKM | |
| SCHEMBL22650171 | 0.78 | KDM4E (0.36) | KDM4ELMNAPKMSMN1; SMN2ALDH1A1 | |
| SCHEMBL22147418 | 0.77 | CNR1 (0.37) | SIRT2KDM4EPIK3CAPIK3CGTDP1 | |
| SCHEMBL21215774 | 0.76 | NPC1 (0.44) | SIRT2KDM4EMAPTLMNAPKM | |
| SCHEMBL20169564 | 0.76 | KDM4E (0.37) | KDM4ELMNASMN1; SMN2ALDH1A1ABL1 | |
| SCHEMBL21098947 | 0.76 | SIRT2 (0.33) | SIRT2KDM4EMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL21215581 | 0.75 | NPC1 (0.45) | KDM4EMAPTLMNAPKMSMN1; SMN2 | |
| SCHEMBL21215640 | 0.74 | CYP11B1 (0.47) | SIRT2KDM4EMAPTLMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190233398-A1 | HETEROCYCLIC COMPOUND, AND ORGANIC LIGHT-EMITTING DEVICE USING SAME | HEESUNG MATERIAL LTD. (KR) | 2019-08-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190233398-A1 | HETEROCYCLIC COMPOUND, AND ORGANIC LIGHT-EMITTING DEVICE USING SAME | CRY1, CRY2, PER2 | SIRT2 158/4885KDM4E 2382/4885MAPT 1063/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.