Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21216241 | 0.84 | KDM4E (0.51) | SIGMAR1KDM4EHSD17B10CHRNB2ADRA2A | |
| SCHEMBL20535067 | 0.84 | KDM4E (0.37) | KDM4EHSD17B10HRH3 | |
| SCHEMBL20535084 | 0.80 | KDM1A (0.39) | — | |
| SCHEMBL20535916 | 0.77 | NR1D1 (0.35) | SIGMAR1KDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL20535903 | 0.74 | KDM1A (0.34) | — | |
| SCHEMBL12694261 | 0.74 | HTT (0.46) | KDM4EHSD17B10HRH3MEN1KMT2A | |
| SCHEMBL24317470 | 0.70 | ADRA2A (0.44) | SIGMAR1MEN1KMT2AADRA2A | |
| SCHEMBL21216287 | 0.69 | JAK2 (0.34) | KDM4EHSD17B10 | |
| Trifluoroacetic Acid SCHEMBL20534760 | 0.68 | HTR5A (0.43) | KDM4EHSD17B10 | |
| SCHEMBL20535219 | 0.67 | KDM4E (0.50) | KDM4EHSD17B10HRH3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019145713-A9 | OLIGONUCLEOTIDE AND NUCLEIC ACID SYNTHESIS | EVONETIX LTD (GB) | 2020-08-06 | — | — | WO | disclosed |
| WO-2019145713-A1 | OLIGONUCLEOTIDE AND NUCLEIC ACID SYNTHESIS | EVONETIX LTD (GB) | 2019-08-01 | — | — | WO | disclosed |