Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 5/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.55 |
| ▸ | NAAA | Q02083 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 2/20 | 0.49 |
| ▸ | THRA | P10827 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2120631 | 0.85 | HPGD (0.68) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL11356018 | 0.80 | MEN1 (0.68) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL2087431 | 0.79 | ALDH1A1 (0.62) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| Hydrochloric Acid SCHEMBL20547794 | 0.78 | ALDH1A1 (0.60) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL10020214 | 0.77 | HPGD (0.79) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL13886655 | 0.77 | MCHR1 (0.61) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL30074611 | 0.77 | HPGD (0.61) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL30074588 | 0.77 | HPGD (0.61) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| Hydrochloric Acid SCHEMBL4449710 | 0.76 | MCHR1 (0.60) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL2614252 | 0.76 | SIGMAR1 (0.68) | NAAANPC1RAB9ATMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9034624-B2 | Process for the synthesis of conjugates of glycosaminoglycanes (GAG) with biologically active molecules, polymeric conjugates and relative uses thereof | FIDIA FARMACEUTICI S.P.A. (IT) | 2015-05-19 | — | — | US | disclosed |
| US-20120114602-A1 | PROCESS FOR THE SYNTHESIS OF CONJUGATES OF GLYCOSAMINOGLYCANES (GAG) WITH BIOLOGICALLY ACTIVE MOLECULES, POLYMERIC CONJUGATES AND RELATIVE USES THEREOF | FIDIA FARMACEUTICI S.P.A. (IT) | 2012-05-10 | — | — | US | disclosed |
| EP-2443156-A1 | PROCESS FOR THE SYNTHESIS OF CONJUGATES OF GLYCOSAMINOGLYCANES (GAG) WITH BIOLOGICALLY ACTIVE MOLECULES, POLYMERIC CONJUGATES AND RELATIVE USES THEREOF | FIDIA FARMACEUTICI S.p.A. (IT) | 2012-04-25 | — | — | EP | disclosed |
| WO-2010145821-A1 | PROCESS FOR THE SYNTHESIS OF CONJUGATES OF GLYCOSAMINOGLYCANES (GAG) WITH BIOLOGICALLY ACTIVE MOLECULES, POLYMERIC CONJUGATES AND RELATIVE USES THEREOF | FIDIA FARMACEUTICI S.P.A. (IT) | 2010-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120114602-A1 | PROCESS FOR THE SYNTHESIS OF CONJUGATES OF GLYCOSAMINOGLYCANES (GAG) WITH BIOLOGICALLY ACTIVE MOLECULES, POLYMERIC CONJUGATES AND RELATIVE USES THEREOF | CD44, HGF, INHA | HDAC1 2665/4885HDAC2 3509/4885HDAC8 2225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.