SCHEMBL2120631

SCHEMBL2120631

CN(C)CCCNC(=O)c1ccccc1

nearest known ligand 0.82

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HPGD P15428 2/20 0.68
▸ NAAA Q02083 1/20 0.63
▸ HDAC3 O15379 1/20 0.63
▸ HDAC4 P56524 1/20 0.63
▸ HDAC1 Q13547 1/20 0.63
▸ HDAC7 Q8WUI4 1/20 0.63
▸ HDAC2 Q92769 1/20 0.63
▸ HDAC10 Q969S8 1/20 0.63
▸ HDAC11 Q96DB2 1/20 0.63
▸ HDAC8 Q9BY41 1/20 0.63
▸ HDAC6 Q9UBN7 1/20 0.63
▸ HDAC9 Q9UKV0 1/20 0.63
▸ HDAC5 Q9UQL6 1/20 0.63
▸ MEN1 O00255 1/20 0.63
▸ KMT2A Q03164 1/20 0.63
▸ SMN1; SMN2 Q16637 1/20 0.62
▸ NPC1 O15118 1/20 0.60
▸ RAB9A P51151 1/20 0.60
▸ KDM4E B2RXH2 3/20 0.59
▸ L3MBTL1 Q9Y468 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11356018 0.94 MEN1 (0.68) HPGDNAAAHDAC3HDAC4HDAC1
SCHEMBL10020214 0.91 HPGD (0.79) HPGDHDAC3HDAC4HDAC1HDAC7
SCHEMBL2614252 0.90 SIGMAR1 (0.68) NAAANPC1RAB9ATMEM97SIGMAR1
SCHEMBL2087431 0.89 ALDH1A1 (0.62) HPGDNAAAHDAC3HDAC4HDAC1
Hydrochloric Acid SCHEMBL20547794 0.88 ALDH1A1 (0.60) HPGDNAAAHDAC3HDAC4HDAC1
SCHEMBL8738694 0.87 MCHR1 (0.66) HPGDHDAC3SMN1; SMN2KDM4EALDH1A1
SCHEMBL18773534 0.86 SMN1; SMN2 (0.60) HPGDMEN1KMT2ASMN1; SMN2KDM4E
Hydrochloric Acid SCHEMBL4454385 0.85 MCHR1 (0.65) HPGDHDAC3SMN1; SMN2ALDH1A1SIGMAR1
SCHEMBL2122336 0.85 HDAC1 (0.58) HPGDNAAAHDAC3HDAC4HDAC1
SCHEMBL8411545 0.85 HPGD (0.70) HPGDHDAC3HDAC4HDAC1HDAC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4416140-A1 SULFONYLPIPERAZINYL COMPOUNDS FOR TREATMENT OF BACTERIAL INFECTIONS F. Hoffmann-La Roche AG (CH) 2024-08-21 — — EP claimed
CN-117597421-A Amine enhanced detergents 雪佛龙奥伦耐有限责任公司 2024-02-23 — — CN claimed
US-11884656-B2 Pyrrole derivatives as PLK1 inhibitors SENTINEL ONCOLOGY LIMITED (GB) 2024-01-30 — — US claimed
WO-2023061617-A1 SULFONYLPIPERAZINYL COMPOUNDS FOR TREATMENT OF BACTERIAL INFECTIONS F. HOFFMANN-LA ROCHE AG (CH) 2023-04-20 — — WO claimed
US-20140141167-A1 POLYMER TIPS NEW YORK UNIVERSITY (US) 2014-05-22 — — US claimed
CN-121824365-A Amphoteric surfactant and application thereof in IGBT cleaning 福州大学 2026-04-10 — — CN disclosed
US-20250043353-A1 BIOMARKERS OF RESPONSE TO SELECTIVE INHIBITORS OF AURORA A KINASE MILLENNIUM PHARM INC (US) 2025-02-06 — — US disclosed
EP-4352188-A1 AMINE-BOOSTED DETERGENT Chevron Oronite Company LLC (US) 2024-04-17 — — EP disclosed
CN-117597421-A Amine enhanced detergents 雪佛龙奥伦耐有限责任公司 2024-02-23 — — CN disclosed
WO-2022259193-A1 AMINE-BOOSTED DETERGENT CHEVRON ORONITE COMPANY LLC (US) 2022-12-15 — — WO disclosed
EP-4019255-A1 DYE INK COMPOSITION, CYAN DYE INK, DYE INK FOR INKJET PRINTING, INKJET PRINTING METHOD, AND DYE AQUEOUS SOLUTION FUJIFILM Corporation (JP) 2022-06-29 — — EP disclosed
CN-110023312-A The Compounds and methods for for preventing malarial parasite from propagating 由卫生与公众服务部部长代表的美利坚合众国 2019-07-16 — — CN disclosed
US-4267102-A Bleomycin group antibiotics NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1981-05-12 — — US disclosed
US-RE30451-E ANTITUMOR AGENTS Zaidan Jojin Biseibutsu Kagaku Kenkyu Kai (JP) 1980-12-16 — — US disclosed
US-4206144-A N,N-Dialkyl-N-aminoalkyl-N-(amino or nitro)phenylalkyl- and N-methyl-N-[3-(amino or nitro)phenoxy-2-hydroxy-1-propyl]-N,N-bis(3-aminopropyl)quaternary ammonium salts STERLING DRUG INC. (US) 1980-06-03 — — US disclosed
US-4146558-A Azo dyestuff intermediate nitro- or aminobenzenes ring-substituted by a quaternized amine alkyl or amino-alkoxy group STERLING DRUG INC. (US) 1979-03-27 — — US disclosed
US-4103092-A Water-soluble quaternary ammonium non-heterocyclic azo dyestuffs STERLING DRUG INC. (US) 1978-07-25 — — US disclosed
US-4065500-A Water-soluble quaternary ammonium azo dyestuffs STERLING DRUG INC. (US) 1977-12-27 — — US disclosed
US-3996282-A Water-soluble quaternary ammonium dyestuffs STERLING DRUG INC. (US) 1976-12-07 — — US disclosed
US-3935182-A Water-soluble quaternary ammonium heterocyclic azo dyestuffs STERLING DRUG INC. (US) 1976-01-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250043353-A1 BIOMARKERS OF RESPONSE TO SELECTIVE INHIBITORS OF AURORA A KINASE WNT1, XPOT, CTNNBL1 HPGD 3671/4885NAAA 4695/4885HDAC3 3981/4885
US-11884656-B2 Pyrrole derivatives as PLK1 inhibitors PLK1, CDK1, AURKC HPGD 2990/4885NAAA 4454/4885HDAC3 562/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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