Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 12/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.62 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.62 |
| ▸ | SERPINA6 | P08185 | 4/20 | 0.62 |
| ▸ | PGR | P06401 | 4/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.62 |
| ▸ | NR3C2 | P08235 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | SHBG | P04278 | 2/20 | 0.62 |
| ▸ | AR | P10275 | 2/20 | 0.57 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.57 |
| ▸ | TNF | P01375 | 1/20 | 0.57 |
| ▸ | IL6 | P05231 | 1/20 | 0.57 |
| ▸ | GLUL | P15104 | 1/20 | 0.57 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.57 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28340921 | 0.94 | HIF1A (0.62) | HIF1AHSD17B10CYP2C19NR3C1SERPINA6 | |
| SCHEMBL28809123 | 0.93 | HIF1A (0.66) | HIF1AHSD17B10CYP2C19NR3C1SERPINA6 | |
| SCHEMBL19463057 | 0.93 | HSD17B10 (0.56) | HIF1AHSD17B10CYP2C19NR3C1SERPINA6 | |
| SCHEMBL6001323 | 0.93 | HIF1A (0.65) | HIF1AHSD17B10CYP2C19NR3C1SERPINA6 | |
| SCHEMBL249836 | 0.92 | HIF1A (0.64) | HIF1AHSD17B10CYP2C19NR3C1SERPINA6 | |
| SCHEMBL14931695 | 0.92 | HIF1A (0.64) | HIF1AHSD17B10CYP2C19NR3C1SERPINA6 | |
| SCHEMBL180226 | 0.92 | HIF1A (0.64) | HIF1AHSD17B10CYP2C19NR3C1SERPINA6 | |
| SCHEMBL11238419 | 0.91 | HIF1A (0.63) | HIF1AHSD17B10CYP2C19NR3C1SERPINA6 | |
| SCHEMBL27698464 | 0.91 | HIF1A (0.63) | HIF1AHSD17B10CYP2C19NR3C1SERPINA6 | |
| SCHEMBL1535104 | 0.91 | HIF1A (0.63) | HIF1AHSD17B10CYP2C19NR3C1SERPINA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150299366-A1 | MOLECULARLY IMPRINTED POLYMER NANOPARTICLES COMPATIBLE WITH BIOLOGICAL SAMPLES AND PREPARATION METHOD THEREOF | NANKAI UNIVERSITY (CN) | 2015-10-22 | — | — | US | claimed |
| CN-116761893-A | Method for transducing immune cells | 艾洛基治疗公司 | 2023-09-15 | — | — | CN | disclosed |
| CN-107920973-B | Surface modification composition | 株式会社LG生活健康 | 2021-05-07 | — | — | CN | disclosed |
| EP-2442771-B1 | SILICONE SCAR TREATMENT PREPARATION | ADVANCED BIO TECH INC (US) | 2020-02-05 | — | — | EP | disclosed |
| US-10053531-B2 | Molecularly imprinted polymer nanoparticles compatible with biological samples and preparation method thereof | NANKAI UNIVERSITY (CN) | 2018-08-21 | — | — | US | disclosed |
| US-9795706-B2 | Silicone scar treatment preparation | ADVANCED BIO-TECHNOLOGIES, INC. (US) | 2017-10-24 | — | — | US | disclosed |
| US-20160213810-A1 | SILICONE SCAR TREATMENT PREPARATION | ADVANCED BIO-TECHNOLOGIES, INC. | 2016-07-28 | — | — | US | disclosed |
| CN-105813578-A | Formulations and methods for increasing or reducing mucus | 弗赛特影像5股份有限公司 | 2016-07-27 | — | — | CN | disclosed |
| CN-105792868-A | Apparatus and methods for low-volume medicament delivery | 豪夫迈·罗氏有限公司 | 2016-07-20 | — | — | CN | disclosed |
| US-9339546-B2 | Silicone scar treatment preparation | ADVANCED BIO-TECHNOLOGIES, INC. (US) | 2016-05-17 | — | — | US | disclosed |
| US-20140314695-A1 | SILICONE SCAR TREATMENT PREPARATION | ADVANCED BIO-TECHNOLOGIES, INC. | 2014-10-23 | — | — | US | disclosed |
| US-8802133-B2 | Silicone scar treatment preparation | ADVANCED BIO-TECHNOLOGIES, INC. (US) | 2014-08-12 | — | — | US | disclosed |
| US-20130183256-A1 | SILICONE SCAR TREATMENT PREPARATION | ADVANCED BIO-TECHNOLOGIES, INC. (US) | 2013-07-18 | — | — | US | disclosed |
| EP-2442771-A1 | SILICONE SCAR TREATMENT PREPARATION | Advanced Bio-Technologies, Inc. (US) | 2012-04-25 | — | — | EP | disclosed |
| US-20100322875-A1 | SILICONE SCAR TREATMENT PREPARATION | ADVANCED BIO-TECHNOLOGIES, INC. (US) | 2010-12-23 | — | — | US | disclosed |
| WO-2010148310-A1 | SILICONE SCAR TREATMENT PREPARATION | ADVANCED BIO-TECHNOLOGIES, INC. (US) | 2010-12-23 | — | — | WO | disclosed |
| CN-1250562-C | Process for preparing hydrocortisone acetate | SHANDONG XINHUA PHARMACEUTICAL (CN) | 2006-04-12 | — | — | CN | disclosed |
| CN-1603333-A | Process for preparing hydrocortisone acetate | SHANDONG XINHUA PHARMACEUTICAL (CN) | 2005-04-06 | — | — | CN | disclosed |
| WO-2001010907-A9 | THERAPEUTIC POLYPEPTIDES AND METHODS FOR USING SAME | UNIV MARYLAND BIOTECH INST (US) | 2002-07-11 | — | — | WO | disclosed |
| US-4252719-A | REMOVAL OF A TERTIARY HYDROGEN FROM A 5-A-STEROID BY CHLORINATING THE STEROID BEING FIRST ESTERIFIED BY AN IODOARYL-CONTAINING ESTERIFICATION AGENT | RESEARCH CORPORATION (US) | 1981-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130183256-A1 | SILICONE SCAR TREATMENT PREPARATION | MMP1, COL1A1, COL2A1 | HIF1A 1964/4885HSD17B10 174/4885CYP2C19 2952/4885 |
| US-20100322875-A1 | SILICONE SCAR TREATMENT PREPARATION | MMP1, COL1A1, COL2A1 | HIF1A 1964/4885HSD17B10 174/4885CYP2C19 2952/4885 |
| US-20160213810-A1 | SILICONE SCAR TREATMENT PREPARATION | MMP1, COL1A1, COL2A1 | HIF1A 1964/4885HSD17B10 174/4885CYP2C19 2952/4885 |
| US-20140314695-A1 | SILICONE SCAR TREATMENT PREPARATION | MMP1, COL1A1, COL2A1 | HIF1A 1964/4885HSD17B10 174/4885CYP2C19 2952/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.