Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MMP14 | P50281 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21228643 | 0.80 | ALDH1A1 (0.39) | ALDH1A1CYP3A4CA2TSHRLMNA | |
| SCHEMBL31627017 | 0.78 | ALDH1A1 (0.46) | ALDH1A1CYP3A4CA2TSHRLMNA | |
| SCHEMBL17193558 | 0.77 | ALDH1A1 (0.37) | ALDH1A1CYP3A4CA2TSHRLMNA | |
| SCHEMBL21220020 | 0.76 | ALDH1A1 (0.44) | ALDH1A1CYP3A4CA2TSHRLMNA | |
| SCHEMBL21228640 | 0.74 | LMNA (0.35) | ALDH1A1TSHRLMNAMAPK1ATM | |
| SCHEMBL21220008 | 0.73 | ALDH1A1 (0.41) | ALDH1A1CYP3A4CA2TSHRLMNA | |
| SCHEMBL21228625 | 0.71 | ABCB11 (0.35) | CYP3A4TSHRLMNAMAPK1 | |
| SCHEMBL110764 | 0.70 | ALDH1A1 (0.81) | ALDH1A1CYP3A4CA2TSHRLMNA | |
| SCHEMBL6578078 | 0.70 | ALDH1A1 (0.72) | ALDH1A1CYP3A4CA2TSHRLMNA | |
| SCHEMBL29832337 | 0.70 | ALDH1A1 (0.81) | ALDH1A1CYP3A4CA2TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10927245-B2 | Non-migratory internal plasticizers attached to a pendant covalent linkage | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-02-23 | — | — | US | disclosed |
| US-20190241727-A1 | NON-MIGRATORY INTERNAL PLASTICIZERS ATTACHED TO A PENDANT COVALENT LINKAGE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-08-08 | — | — | US | disclosed |