Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | PPM1B | O75688 | 1/20 | 0.35 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.35 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PPP5C | P53041 | 1/20 | 0.35 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6727362 | 0.86 | L3MBTL1 (0.33) | LMNASMN1; SMN2KDM4EGMNNPPM1B | |
| SCHEMBL18873867 | 0.86 | L3MBTL1 (0.33) | LMNASMN1; SMN2KDM4EGMNNPPM1B | |
| SCHEMBL447364 | 0.82 | NOS3 (0.31) | — | |
| SCHEMBL2122883 | 0.82 | L3MBTL1 (0.40) | LMNASMN1; SMN2KDM4EGMNNPPM1B | |
| SCHEMBL3753452 | 0.81 | LMNA (0.44) | LMNASMN1; SMN2KDM4EGMNNPPM1B | |
| SCHEMBL13058468 | 0.78 | LMNA (0.36) | LMNASMN1; SMN2KDM4EGMNNPPM1B | |
| SCHEMBL15839586 | 0.76 | KDM4E (0.30) | LMNASMN1; SMN2KDM4ETDP1TP53 | |
| SCHEMBL2685999 | 0.76 | LMNA (0.33) | LMNASMN1; SMN2KDM4ETDP1TP53 | |
| SCHEMBL13255675 | 0.76 | LMNA (0.33) | LMNASMN1; SMN2KDM4ETDP1TP53 | |
| SCHEMBL6727392 | 0.74 | L3MBTL1 (0.35) | SMN1; SMN2RAB9ATP53L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2185564-B1 | Herbicidally active cyclopentanedione compounds and derivatives thereof | SYNGENTA LTD (GB) | 2014-06-18 | — | — | EP | disclosed |
| US-8754242-B2 | Herbicides | SYNGENTA CROP PROTECTION LLC (US) | 2014-06-17 | — | — | US | disclosed |
| US-20120094832-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120094832-A1 | NOVEL HERBICIDES | DDT, CYP1B1, CYP1A1 | LMNA 4671/4885SMN1; SMN2 2924/4885KDM4E 1070/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.