SCHEMBL212325

SCHEMBL212325

[CH]c1ccc(O)c(OC)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.61
SLC22A6 Q4U2R8 1/20 0.53
SLC22A8 Q8TCC7 1/20 0.53
MEN1 O00255 1/20 0.53
RAB9A P51151 1/20 0.53
KMT2A Q03164 1/20 0.53
TRPA1 O75762 1/20 0.52
TRIM24 O15164 1/20 0.52
ALDH1A1 P00352 1/20 0.52
HPGD P15428 1/20 0.52
ALDH5A1 P51649 1/20 0.52
ABAT P80404 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
TRIM33 Q9UPN9 1/20 0.52
HTT P42858 1/20 0.52
CA2 P00918 3/20 0.50
TSHR P16473 3/20 0.50
TAAR1 Q96RJ0 2/20 0.50
NR3C1 P04150 2/20 0.50
TYR P14679 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL364214 1.00 MAOB (0.61) MAOBSLC22A6SLC22A8MEN1RAB9A
SCHEMBL497561 0.78 CA2 (0.54) ALDH1A1CA2TSHRNR3C1MAPK1
SCHEMBL497560 0.78 CA2 (0.54) ALDH1A1CA2TSHRNR3C1MAPK1
SCHEMBL29373807 0.76 MAOB (1.00) MAOBSLC22A6SLC22A8MEN1RAB9A
SCHEMBL3693339 0.76 MAOB (0.67) MAOBSLC22A6SLC22A8MEN1RAB9A
SCHEMBL62784 0.76 MAOB (1.00) MAOBSLC22A6SLC22A8MEN1RAB9A
Methoxymethane SCHEMBL10894687 0.74 MAOB (0.95) MAOBSLC22A6SLC22A8MEN1RAB9A
SCHEMBL4386820 0.74 MAOB (0.64) MAOBSLC22A6SLC22A8MEN1RAB9A
SCHEMBL595280 0.74 MAOB (0.64) MAOBSLC22A6SLC22A8MEN1RAB9A
SCHEMBL8186220 0.74 MAOB (0.95) MAOBSLC22A6SLC22A8MEN1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130108565-A1 TANNING ENHANCERS AND SELF-TANNING SUBSTANCES MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2013-05-02 US claimed
WO-2012007095-A2 TANNING PROMOTER AND SELF-TANNING SUBSTANCES MERCK PATENT GMBH (DE) 2012-01-19 WO claimed
US-7846471-B2 Rumen protected essential amino acids ZINPRO CORPORATION (US) 2010-12-07 US claimed
US-7704521-B2 Rumen protected essential amino acids ZINPRO CORPORATION (US) 2010-04-27 US claimed
EP-1282397-B1 USE OF COMPOUNDS CONTAINING A THIO-ETHER, SULPHOXIDE OR SULPHONE FUNCTION AS COSMETIC ANTI-POLLUTION AGENT OREAL (FR) 2005-05-04 EP claimed
EP-0858319-B1 USE OF CARBOXYLIC ACIDS HAVING A SULPHUR FUNCTION FOR PROMOTING SKIN EXFOLIATION OR STIMULATING EPIDERMAL REGENERATION OREAL (FR) 2003-07-23 EP claimed
US-20030036489-A1 Consumable composition comprising perfumed particles and article containing the same THE PROCTER & GAMBLE COMPANY 2003-02-20 US claimed
EP-1282397-A1 USE OF COMPOUNDS CONTAINING A THIO-ETHER, SULPHOXIDE OR SULPHONE FUNCTION AS COSMETIC ANTI-POLLUTION AGENT L'OREAL (FR) 2003-02-12 EP claimed
WO-2002090481-A1 COMPOSITIONS AND ARTICLES FOR EFFECTIVE DEPOSITION OF PERFUME THE PROCTER & GAMBLE COMPANY (US) 2002-11-14 WO claimed
WO-2001087261-A1 USE OF COMPOUNDS CONTAINING A THIO-ETHER, SULPHOXIDE OR SULPHONE FUNCTION AS COSMETIC ANTI-POLLUTION AGENT L'OREAL (FR) 2001-11-22 WO claimed
EP-0858319-A1 USE OF CARBOXYLIC ACIDS HAVING A SULPHUR FUNCTION FOR PROMOTING SKIN EXFOLIATION OR STIMULATING EPIDERMAL REGENERATION L'OREAL (FR) 1998-08-19 EP claimed
WO-1997016165-A1 USE OF CARBOXYLIC ACIDS HAVING A SULPHUR FUNCTION FOR PROMOTING SKIN EXFOLIATION OR STIMULATING EPIDERMAL REGENERATION L'OREAL (FR) 1997-05-09 WO claimed
JP-56059818-A None JP disclosed
US-20220227694-A1 Method of Depolymerising Phenolic Polymers STELLENBOSCH UNIVERSITY (ZA) 2022-07-21 US disclosed
EP-1760142-B2 Laundry Scent Customization PROCTER & GAMBLE (US) 2020-07-15 EP disclosed
WO-2014102368-A1 RECOMBINANT HOST CELL FOR BIOSYNTHETIC PRODUCTION EVIAGENICS S.A. (FR) 2014-07-03 WO disclosed
WO-1999047107-A1 METHOD FOR PERMING AND DYEING HAIR HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1999-09-23 WO disclosed
EP-0858319-A1 USE OF CARBOXYLIC ACIDS HAVING A SULPHUR FUNCTION FOR PROMOTING SKIN EXFOLIATION OR STIMULATING EPIDERMAL REGENERATION L'OREAL (FR) 1998-08-19 EP disclosed
WO-1997016165-A1 USE OF CARBOXYLIC ACIDS HAVING A SULPHUR FUNCTION FOR PROMOTING SKIN EXFOLIATION OR STIMULATING EPIDERMAL REGENERATION L'OREAL (FR) 1997-05-09 WO disclosed
JP-S5659818-A PRODUCTION OF 1-ARYL-4-CARBOETHOXY-5-(3'-METHOXY-4'-METHACRYLOYLOXY)-2-PYRROLIDINONE COPOLYMER KINKIDAIGAKU 1981-05-23 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220227694-A1 Method of Depolymerising Phenolic Polymers DCXR, GRHPR, HPD MAOB 972/4885SLC22A6 4723/4885SLC22A8 4632/4885
US-20130108565-A1 TANNING ENHANCERS AND SELF-TANNING SUBSTANCES TYR, DERA, HAAO MAOB 103/4885SLC22A6 307/4885SLC22A8 625/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.