Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 4/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ITGAV | P06756 | 4/20 | 0.35 |
| ▸ | ITGB5 | P18084 | 4/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26066647 | 0.83 | FOLH1 (0.42) | FOLH1ALDH1A1ITGAVITGB5MAOA | |
| SCHEMBL26066648 | 0.79 | FOLH1 (0.41) | FOLH1ALDH1A1ITGAVITGB5MAOA | |
| SCHEMBL21232781 | 0.79 | ITGAV (0.40) | ALDH1A1ITGAVITGB5MAOAMAOB | |
| SCHEMBL15257805 | 0.74 | MAOA (0.43) | ALDH1A1ITGAVITGB5MAOAMAOB | |
| SCHEMBL21063617 | 0.72 | MAOA (0.47) | ALDH1A1ITGAVITGB5MAOAMAOB | |
| SCHEMBL18632997 | 0.72 | MAOA (0.44) | ALDH1A1ITGAVITGB5MAOAMAOB | |
| SCHEMBL25013972 | 0.71 | GBA1 (0.57) | GBA1MAOA | |
| SCHEMBL16188469 | 0.71 | DGAT1 (0.48) | FOLH1GBA1 | |
| SCHEMBL26066699 | 0.70 | HDAC1 (0.43) | FOLH1GBA1MAOAMAOBGAA | |
| SCHEMBL16188527 | 0.70 | DGAT1 (0.50) | FOLH1GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019150138-A1 | CONJUGATES OF CYCLODEXTRINS AND DEFERASIROX OR ANALOGUES THEREOF | THE UNIVERSITY OF SUSSEX (GB) | 2019-08-08 | — | — | WO | disclosed |