Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | CD38 | P28907 | 1/20 | 0.33 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.32 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22951414 | 0.77 | TBXAS1 (0.36) | CYP11B2TBXAS1CD38IMPDH2PDE10A | |
| SCHEMBL21233347 | 0.73 | KDM4E (0.43) | CYP11B2CREBBPKDM4EALDH1A1POLB | |
| SCHEMBL21233159 | 0.70 | CYP11B2 (0.44) | CYP11B2BRD4CREBBPPRMT5WDR77 | |
| SCHEMBL21233154 | 0.70 | ALDH1A1 (0.41) | CYP11B2BRD4CREBBPKDM4EALDH1A1 | |
| SCHEMBL21233332 | 0.69 | TBXAS1 (0.41) | CYP11B2TBXAS1CD38ALDH1A1PDE10A | |
| SCHEMBL21233164 | 0.69 | CYP11B2 (0.39) | CYP11B2BRD4CREBBPKDM4EALDH1A1 | |
| SCHEMBL25235606 | 0.67 | BRD4 (0.38) | CYP11B2BRD4CREBBPKDM4EALDH1A1 | |
| SCHEMBL571374 | 0.67 | HDAC8 (0.50) | TBXAS1CD38IMPDH2PRMT5WDR77 | |
| SCHEMBL21233338 | 0.67 | CYP11B2 (0.51) | CYP11B2BRD4CREBBPPRMT5WDR77 | |
| SCHEMBL15345127 | 0.67 | CYP11B2 (0.66) | CYP11B2BRD4CREBBPPRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019148851-A1 | FIVE-MEMBERED RING-SUBSTITUTED PYRIDAZINOL COMPOUND AND DERIVATIVES THEREOF, PREPARATION METHOD, HERBICIDAL COMPOSITION, AND APPLICATION | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |
| WO-2019149260-A1 | PYRIDAZINOL COMPOUND, DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |