Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
| ▸ | IDE | P14735 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30952445 | 0.82 | TRPM5 (0.39) | TRPM5BRD4 | |
| SCHEMBL8788122 | 0.82 | LMNA (0.47) | LMNARAB9A | |
| SCHEMBL693306 | 0.82 | TRPM5 (0.39) | TRPM5BRD4 | |
| SCHEMBL4659346 | 0.82 | ALDH1A1 (0.41) | TRPM5HDAC6LMNA | |
| SCHEMBL22951427 | 0.81 | ALDH1A1 (0.41) | TRPM5BRD4LMNAPOLB | |
| Hydrochloric Acid SCHEMBL27845581 | 0.81 | ALDH1A1 (0.40) | TRPM5HDAC6BRD4LMNA | |
| Benzo[D]Isoxazole SCHEMBL5697385 | 0.71 | CYP3A4 (0.36) | NPC1SMN1; SMN2PTGS2LMNAATM | |
| SCHEMBL12508320 | 0.71 | AKR1C3 (0.58) | AKR1C3AKR1C2G6PDIDESMN1; SMN2 | |
| SCHEMBL2001766 | 0.71 | TRPM5 (0.37) | TRPM5 | |
| SCHEMBL2616766 | 0.71 | CYP2A6 (0.44) | TRPM5NPC1SMN1; SMN2POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019149260-A1 | PYRIDAZINOL COMPOUND, DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |
| WO-2019148851-A1 | FIVE-MEMBERED RING-SUBSTITUTED PYRIDAZINOL COMPOUND AND DERIVATIVES THEREOF, PREPARATION METHOD, HERBICIDAL COMPOSITION, AND APPLICATION | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |