Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | F2 | P00734 | 2/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22952755 | 0.78 | HTR2C (0.44) | HTR2CHTR2AF2PDE10AHTR2B | |
| SCHEMBL13430366 | 0.76 | KDM4E (0.52) | ALDH1A1CYP1A2SMN1; SMN2PDE10ATDP1 | |
| SCHEMBL1456807 | 0.73 | GOT1 (0.46) | HTR2CALDH1A1CYP1A2SMN1; SMN2CYP11B2 | |
| SCHEMBL29442588 | 0.73 | GOT1 (0.46) | HTR2CALDH1A1CYP1A2SMN1; SMN2CYP11B2 | |
| SCHEMBL30792004 | 0.73 | GOT1 (0.46) | HTR2CALDH1A1CYP1A2SMN1; SMN2CYP11B2 | |
| SCHEMBL15293904 | 0.71 | KDM4E (0.40) | HTR2CALDH1A1CYP1A2CYP3A4SMN1; SMN2 | |
| SCHEMBL26847603 | 0.70 | PDE10A (0.40) | HTR2CALDH1A1CYP1A2CYP3A4SMN1; SMN2 | |
| SCHEMBL5280031 | 0.69 | RAB9A (0.51) | ALDH1A1SMN1; SMN2CYP11B2 | |
| SCHEMBL21233170 | 0.69 | ALDH1A1 (0.37) | ALDH1A1CYP1A2CYP3A4SMN1; SMN2APOBEC3G | |
| SCHEMBL19145066 | 0.68 | DYRK1A (0.41) | ALDH1A1CYP1A2CYP3A4SMN1; SMN2CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019148851-A1 | FIVE-MEMBERED RING-SUBSTITUTED PYRIDAZINOL COMPOUND AND DERIVATIVES THEREOF, PREPARATION METHOD, HERBICIDAL COMPOSITION, AND APPLICATION | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |
| WO-2019149260-A1 | PYRIDAZINOL COMPOUND, DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |