SCHEMBL21234690

SCHEMBL21234690

CN(CCO)c1cc2c(s1)-c1sc(/C=C(\C#N)C(=O)OC(C)(C)C)cc1[Si]2(C)C

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
KMT2A Q03164 1/20 0.32
RPS6KA3 P51812 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21234930 0.83 MEN1 (0.32) MEN1ALDH1A1KMT2ARPS6KA3
SCHEMBL21160465 0.83 MEN1 (0.32) MEN1ALDH1A1KMT2ARPS6KA3
SCHEMBL21036998 0.82 RPS6KA3 (0.36) MEN1ALDH1A1KMT2ARPS6KA3
SCHEMBL21037880 0.81 MEN1 (0.34) MEN1ALDH1A1KMT2ARPS6KA3
SCHEMBL21160619 0.80 RPS6KA3 (0.34) MEN1ALDH1A1KMT2ARPS6KA3
SCHEMBL21234705 0.77 MAPT (0.35)
SCHEMBL21036841 0.76 KMT2A (0.41) MEN1ALDH1A1KMT2ARPS6KA3
SCHEMBL21037017 0.75 KDM4E (0.32) ALDH1A1
SCHEMBL21037280 0.74 APP (0.38) MEN1ALDH1A1KMT2ARPS6KA3
SCHEMBL24605694 0.74 SIGMAR1 (0.31) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11365203-B2 Fluorescent dye and preparation method and use thereof FLUORESCENCE DIAGNOSIS (SHANGHAI) BIOTECH COMPANY LTD. (CN) 2022-06-21 US disclosed
US-20190241584-A1 FLUORESCENT DYE AND PREPARATION METHOD AND USE THEREOF EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2019-08-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190241584-A1 FLUORESCENT DYE AND PREPARATION METHOD AND USE THEREOF DNASE1, POLRMT, DCLRE1B MEN1 3709/4885ALDH1A1 422/4885KMT2A 3545/4885
US-11365203-B2 Fluorescent dye and preparation method and use thereof DNASE1, POLRMT, DCLRE1B MEN1 3709/4885ALDH1A1 422/4885KMT2A 3545/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.