Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | CA12 | O43570 | 3/20 | 0.52 |
| ▸ | CA1 | P00915 | 3/20 | 0.52 |
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | CA7 | P43166 | 3/20 | 0.52 |
| ▸ | CA9 | Q16790 | 3/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | CA3 | P07451 | 2/20 | 0.52 |
| ▸ | CA4 | P22748 | 2/20 | 0.52 |
| ▸ | CA6 | P23280 | 2/20 | 0.52 |
| ▸ | CA5A | P35218 | 2/20 | 0.52 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | SELL | P14151 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | SELP | P16109 | 1/20 | 0.52 |
| ▸ | FUT4 | P22083 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16077680 | 0.89 | CA12 (0.64) | ALDH1A1CA12CA1CA2CA7 | |
| SCHEMBL4365225 | 0.86 | SHBG (0.53) | ALDH1A1CA12CA1CA2CA7 | |
| SCHEMBL16077698 | 0.86 | TTR (0.67) | ALDH1A1CA12CA1CA2CA7 | |
| SCHEMBL10452005 | 0.83 | PKM (0.45) | ALDH1A1KDM4ELMNAMAPTHPGD | |
| SCHEMBL13851422 | 0.81 | CA12 (0.70) | ALDH1A1CA12CA1CA2CA7 | |
| SCHEMBL5907906 | 0.81 | ALDH1A1 (0.64) | ALDH1A1CA12CA1CA2CA7 | |
| SCHEMBL1237714 | 0.81 | TPMT (0.46) | ALDH1A1CA12CA1CA2CA7 | |
| SCHEMBL4109854 | 0.76 | PKM (0.69) | CA12CA1CA2CA7CA9 | |
| SCHEMBL28503260 | 0.76 | ALDH1A1 (0.58) | ALDH1A1CA12CA1CA2CA7 | |
| Gallic Acid SCHEMBL7774087 | 0.76 | KDM4E (0.63) | ALDH1A1CA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120094939-A1 | ANTI-VIRAL COMPOUNDS, COMPOSITIONS AND METHODS | TRUSTEES OF BOSTON UNIVERSITY | 2012-04-19 | — | — | US | disclosed |
| WO-2008124571-A2 | ANTI-VIRAL COMPOUNDS, COMPOSITIONS AND METHODS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2008-10-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120094939-A1 | ANTI-VIRAL COMPOUNDS, COMPOSITIONS AND METHODS | HAVCR2, EIF2AK2, RPL35 | ALDH1A1 1203/4885CA12 2229/4885CA1 4597/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.