SCHEMBL10452005

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2123786	0.83	ALDH1A1 (0.59)	PKMKDM4ECASP6ALDH1A1PTGS2
	SCHEMBL8092896	0.80	GABRA1 (0.48)	PKMALDH1A1FASNCNR2LMNA
	SCHEMBL11061298	0.76	KDM4E (0.59)	PKMKDM4EALDH1A1CNR2LMNA
	SCHEMBL10548309	0.73	PKM (0.48)	PKMALDH1A1PTGS2ESR1ESR2
	SCHEMBL2123617	0.73	CA12 (0.61)	ALDH1A1ESR1ESR2LMNAMAPT
	SCHEMBL16077680	0.73	CA12 (0.64)	PKMKDM4ECASP6ALDH1A1CYBB
	SCHEMBL835866	0.73	KDM4E (0.46)	PKMKDM4ECASP6ALDH1A1SHBG
	SCHEMBL26132747	0.73	KDM4E (0.46)	PKMKDM4ECASP6ALDH1A1SHBG
	SCHEMBL9999531	0.73	ACHE (0.48)	PKMKDM4ECASP6ALDH1A1SHBG
	SCHEMBL27420314	0.72	MAPT (0.42)	PKMKDM4EALDH1A1FASNLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.