Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 14/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | HPGD | P15428 | 5/20 | 0.39 |
| ▸ | GLA | P06280 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13868312 | 0.82 | KDM4E (0.43) | KDM4ELMNAALDH1A1HPGDGLA | |
| SCHEMBL15958871 | 0.76 | TRPV4 (0.42) | KDM4ELMNAALDH1A1HPGDGLA | |
| SCHEMBL22695033 | 0.75 | RXRA (0.39) | TDP1RXRARXRBRXRG | |
| SCHEMBL24854679 | 0.74 | KDM4E (0.43) | KDM4ELMNAUSP2ALDH1A1HPGD | |
| SCHEMBL20186996 | 0.74 | KDM4E (0.43) | KDM4ELMNAUSP2ALDH1A1HPGD | |
| SCHEMBL16483020 | 0.74 | KDM4E (0.46) | KDM4ELMNAUSP2ALDH1A1HPGD | |
| SCHEMBL10225858 | 0.73 | SIGMAR1 (0.39) | RXRARXRBRXRG | |
| SCHEMBL23557907 | 0.72 | ALDH1A1 (0.46) | ALDH1A1TP53POLBTDP1RXRA | |
| SCHEMBL21667290 | 0.71 | KDM4E (0.43) | KDM4ELMNAUSP2ALDH1A1HPGD | |
| SCHEMBL25991271 | 0.70 | KDM4E (0.43) | KDM4EALDH1A1HPGDGLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019149260-A1 | PYRIDAZINOL COMPOUND, DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |