Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | BCR | P11274 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | PRKDC | P78527 | 1/20 | 0.32 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15156739 | 0.82 | LMNA (0.47) | LMNAHSD17B10KDM4EMAPK1ALDH1A1 | |
| SCHEMBL21233319 | 0.78 | RAB9A (0.44) | HTTKDM4EALDH1A1PKMGAA | |
| SCHEMBL4381704 | 0.69 | — | — | |
| SCHEMBL12984658 | 0.69 | MAPK1 (0.56) | LMNAHTTKDM4EMAPK1ALDH1A1 | |
| SCHEMBL17382010 | 0.69 | LMNA (0.41) | LMNAHTTKDM4EALDH1A1GAA | |
| SCHEMBL20705348 | 0.69 | KMO (0.42) | LMNAKCNH2HSD17B10HTTALDH1A1 | |
| SCHEMBL20705347 | 0.69 | KMO (0.42) | LMNAKCNH2HSD17B10HTTALDH1A1 | |
| SCHEMBL2935295 | 0.67 | — | — | |
| SCHEMBL17382258 | 0.67 | LMNA (0.40) | LMNAHTTABL1BCRKDM4E | |
| SCHEMBL23138139 | 0.66 | CYP1A2 (0.39) | KCNH2HSD17B10KDM4EMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019149260-A1 | PYRIDAZINOL COMPOUND, DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |