Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT1 | P30419 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 9/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21233187 | 0.71 | ALDH1A1 (0.39) | ALDH1A1CYP3A4SMN1; SMN2CYP1A2APOBEC3G | |
| SCHEMBL21241208 | 0.69 | IDO1 (0.45) | IDO1ALDH1A1FKBP5CYP3A4CYP11B2 | |
| SCHEMBL21233334 | 0.68 | PIM1 (0.37) | ALDH1A1CYP3A4SMN1; SMN2CYP1A2APOBEC3G | |
| SCHEMBL21233176 | 0.68 | COMT (0.49) | ALDH1A1CYP3A4SMN1; SMN2CYP1A2APOBEC3G | |
| SCHEMBL21233172 | 0.68 | ALDH1A1 (0.36) | ALDH1A1CYP3A4SMN1; SMN2CYP1A2APOBEC3G | |
| SCHEMBL9209126 | 0.68 | CCR1 (0.55) | IDO1ALDH1A1FKBP5CYP3A4SMN1; SMN2 | |
| SCHEMBL21233332 | 0.68 | TBXAS1 (0.41) | ALDH1A1CYP3A4SMN1; SMN2CYP1A2CYP11B1 | |
| SCHEMBL21233191 | 0.67 | ALDH1A1 (0.38) | ALDH1A1CYP3A4SMN1; SMN2CYP1A2APOBEC3G | |
| SCHEMBL7194641 | 0.66 | IDO1 (0.59) | IDO1ALDH1A1FKBP5CYP3A4SMN1; SMN2 | |
| SCHEMBL21233320 | 0.66 | IDO1 (0.40) | IDO1ALDH1A1CYP3A4SMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019149260-A1 | PYRIDAZINOL COMPOUND, DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |