Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | CNR2 | P34972 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25894216 | 0.84 | ALDH1A1 (0.60) | MAPTTSHRHTTMAPK1POLB | |
| SCHEMBL29952860 | 0.83 | ALDH1A1 (0.65) | MAPTTSHRMAPK1POLBALDH1A1 | |
| SCHEMBL3349361 | 0.81 | KEAP1 (0.51) | MAPTTSHRHTTMAPK1CNR2 | |
| Bicarbonate SCHEMBL11138673 | 0.79 | CNR2 (0.56) | MAPTTSHRHTTMAPK1CNR2 | |
| SCHEMBL28300064 | 0.77 | MAPT (0.48) | MAPTTSHRHTTMAPK1POLB | |
| SCHEMBL17689350 | 0.77 | ALDH1A1 (0.46) | MAPTTSHRHTTMAPK1CNR2 | |
| SCHEMBL43704 | 0.76 | ALDH1A1 (0.61) | MAPTTSHRHTTMAPK1CNR2 | |
| SCHEMBL29957410 | 0.76 | ALDH1A1 (0.47) | MAPTHTTMAPK1ALDH1A1MEN1 | |
| SCHEMBL31037870 | 0.75 | MAPT (0.49) | MAPTTSHRHTTMAPK1CNR2 | |
| Alcohol SCHEMBL9810838 | 0.74 | ALDH1A1 (0.54) | MAPTTSHRHTTMAPK1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023138362-A1 | WEE1 INHIBITOR, PREPARATION THEREFOR, AND USE THEREOF | 江苏天士力帝益药业有限公司 | 2023-07-27 | — | — | WO | disclosed |
| WO-2019149260-A1 | PYRIDAZINOL COMPOUND, DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |