Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SDHB | P21912 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | ALPI | P09923 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21241512 | 0.84 | ADORA2A (0.48) | ADORA2AADORA1ALDH1A1SDHBCYP11B2 | |
| SCHEMBL21241364 | 0.83 | SDHB (0.39) | ADORA2AADORA1ALDH1A1SDHBPTGS2 | |
| SCHEMBL21241363 | 0.70 | ADORA2A (0.45) | ADORA2AADORA1ALDH1A1PTGS2PTGS1 | |
| SCHEMBL21241500 | 0.70 | ADORA2A (0.45) | ADORA2AADORA1ALDH1A1LMNA | |
| SCHEMBL21241087 | 0.68 | TRPA1 (0.41) | PTGS2PTGS1 | |
| SCHEMBL13863713 | 0.67 | CYP11B1 (0.46) | CYP11B1CYP11B2PTGS2PTGS1AR | |
| SCHEMBL13002538 | 0.67 | CYP11B1 (0.46) | CYP11B1CYP11B2PTGS2PTGS1AR | |
| SCHEMBL30525470 | 0.67 | ENPP1 (0.42) | ALDH1A1SDHBCYP11B1CYP11B2LMNA | |
| SCHEMBL24602339 | 0.66 | RPS6KA3 (0.45) | ALDH1A1CYP11B1CYP11B2PTGS2HDAC6 | |
| SCHEMBL21241521 | 0.66 | ALDH1A1 (0.49) | ADORA2AADORA1ALDH1A1PTGS1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019149260-A1 | PYRIDAZINOL COMPOUND, DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |