Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 15/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22861597 | 1.00 | FKBP1A (0.52) | FKBP1AKDM4EALDH1A1TNKS2 | |
| SCHEMBL22861533 | 0.97 | FKBP1A (0.53) | FKBP1AKDM4EALDH1A1TNKS2 | |
| SCHEMBL21241612 | 0.97 | FKBP1A (0.53) | FKBP1AKDM4EALDH1A1TNKS2 | |
| SCHEMBL21241611 | 0.89 | FKBP1A (0.49) | FKBP1AKDM4EALDH1A1 | |
| SCHEMBL22861528 | 0.89 | FKBP1A (0.49) | FKBP1AKDM4EALDH1A1 | |
| SCHEMBL22861532 | 0.82 | L3MBTL1 (0.47) | KDM4EALDH1A1 | |
| SCHEMBL21241652 | 0.82 | L3MBTL1 (0.47) | KDM4EALDH1A1 | |
| SCHEMBL21241651 | 0.82 | FKBP1A (0.50) | FKBP1AALDH1A1 | |
| SCHEMBL22861588 | 0.82 | FKBP1A (0.50) | FKBP1AALDH1A1 | |
| SCHEMBL8545744 | 0.79 | L3MBTL1 (0.48) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019152527-A1 | PIPECOLIC ESTERS FOR INHIBITION OF THE PROTEASOME | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2019-08-08 | — | — | WO | disclosed |