Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8547628 | 0.99 | L3MBTL1 (0.47) | L3MBTL1MAPK1OPRK1TDP1KDM4E | |
| SCHEMBL11452675 | 0.82 | MAPK1 (0.44) | L3MBTL1MAPK1OPRK1TDP1KDM4E | |
| SCHEMBL21241652 | 0.79 | L3MBTL1 (0.47) | L3MBTL1MAPK1TDP1KDM4EKMT2A | |
| SCHEMBL22861532 | 0.79 | L3MBTL1 (0.47) | L3MBTL1MAPK1TDP1KDM4EKMT2A | |
| SCHEMBL22861597 | 0.79 | FKBP1A (0.52) | KDM4EALDH1A1 | |
| SCHEMBL21241653 | 0.79 | FKBP1A (0.52) | KDM4EALDH1A1 | |
| SCHEMBL21241611 | 0.77 | FKBP1A (0.49) | L3MBTL1TDP1KDM4EKMT2AALDH1A1 | |
| SCHEMBL22861528 | 0.77 | FKBP1A (0.49) | L3MBTL1TDP1KDM4EKMT2AALDH1A1 | |
| SCHEMBL16577350 | 0.77 | NPC1 (0.47) | KDM4EKMT2AALDH1A1MEN1TP53 | |
| SCHEMBL5732981 | 0.77 | ALDH1A1 (0.52) | L3MBTL1KMT2AALDH1A1MEN1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564924-B1 | 2-Oxoethyl derivatives as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | claimed |
| US-5686424-A | FOR TREATING INFLAMMATION | MILES INC. (US) | 1997-11-11 | — | — | US | disclosed |