SCHEMBL294143

SCHEMBL294143

COC(=O)c1ccc(OC)cc1O

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.72
CA1 P00915 2/20 0.72
CA2 P00918 2/20 0.72
CA7 P43166 2/20 0.72
CA9 Q16790 2/20 0.72
CA14 Q9ULX7 2/20 0.72
NPC1 O15118 2/20 0.72
RAB9A P51151 2/20 0.72
PDK2 Q15119 1/20 0.72
PDK4 Q16654 1/20 0.72
HPGD P15428 3/20 0.70
CYP3A4 P08684 3/20 0.70
MAPK1 P28482 3/20 0.70
ALDH1A1 P00352 2/20 0.70
GAA P10253 1/20 0.62
CYP2C19 P33261 4/20 0.62
LMNA P02545 4/20 0.62
CYP1A2 P05177 3/20 0.62
PGR P06401 2/20 0.62
SLC6A2 P23975 2/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dioxane SCHEMBL28341218 0.90 NPC1 (0.60) CA12CA1CA2CA7CA9
SCHEMBL17904269 0.87 NPC1 (0.70) CA12CA1CA2CA7CA9
SCHEMBL14292891 0.85 LMNA (0.77) CA12CA1CA2CA7CA9
SCHEMBL12634385 0.85 APP (0.64) CA12CA1CA2CA7CA9
SCHEMBL3467699 0.85 NPC1 (0.54) CA12CA1CA2CA7CA9
Methyl 2-Hydroxy-5-Methoxybenzoate SCHEMBL29709382 0.85 CA1 (0.72) CA12CA1CA2CA7CA9
SCHEMBL11324398 0.85 NPC1 (0.72) CA12CA1CA2CA7CA9
Methyl 2-Hydroxy-5-Methoxybenzoate SCHEMBL643758 0.85 CA1 (0.72) CA12CA1CA2CA7CA9
SCHEMBL4212043 0.84 MAOB (0.58) CA12CA1CA2CA7CA9
Methyl 2,4-Dihydroxybenzoate SCHEMBL30917273 0.84 CA12 (1.00) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 570 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118852129-A Preparation method and application of triazole feed additive with anti-inflammatory activity designed based on deep learning technology 河南湾流生物科技有限公司 2024-10-29 CN claimed
US-20230148641-A1 FLAVOR COMPOSITION FIRMENICH SA (CH) 2023-05-18 US claimed
EP-4125427-A1 FLAVOR COMPOSITION Firmenich SA (CH) 2023-02-08 EP claimed
WO-2021198199-A1 FLAVOR COMPOSITION FIRMENICH SA (CH) 2021-10-07 WO claimed
CN-109541045-A The active components content assaying method such as a kind of halimasch and its product Asclerol 吉林农业大学 2019-03-29 CN claimed
US-10191398-B2 Electrophotographic photoconductor, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2019-01-29 US claimed
EP-3710462-B1 BRARTEMICIN ANALOGUES VICTORIA LINK LTD (NZ) 2026-05-13 EP disclosed
US-20260101914-A1 VANILLA COMPOSITION FIRMENICH & CIE (CH) 2026-04-16 US disclosed
US-12576055-B2 Disease detection and treatment based on trimethyl-lysine levels THE CLEVELAND CLINIC FOUNDATION (US) 2026-03-17 US disclosed
EP-4680039-A1 COMPOSITIONS FOR REDUCING OFF NOTES AND USES THEREOF DSM-Firmenich AG (CH) 2026-01-21 EP disclosed
US-20250377364-A1 REAGENT, METHOD, AND DEVICE FOR DETECTING ALBUMIN NEC CORPORATION (JP) 2025-12-11 US disclosed
WO-2025106974-A1 PRODRUG MOIETIES AND COMPOUNDS COMPRISING THE SAME THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2025-05-22 WO disclosed
WO-2024251755-A1 COMPOSITIONS FOR REDUCING OFF NOTES AND USES THEREOF DSM-FIRMENICH AG (CH) 2024-12-12 WO disclosed
US-4604390-A FUNGICIDES, ANTITUMOR AGENTS WARNER-LAMBERT COMPANY (US) 1986-08-05 US disclosed
EP-0187487-A1 Benzothiophenes and benzofurans having antiallergic activity WARNER-LAMBERT COMPANY (US) 1986-07-16 EP disclosed
EP-0172632-A1 Benzopyrano[4,3,2-cd]indazole compounds, processes for their production and pharmaceutical compositions comprising the compounds WARNER-LAMBERT COMPANY (US) 1986-02-26 EP disclosed
US-4426332-A FROM A 1,3-CYCLOHEXANEDIONE AND OXYGEN, COPPER CATALYST, HYDROGEN HALIDE OR THIONYL CHLORIDE, SOLVENT BASF AKTIENGESELLSCHAFT (DE) 1984-01-17 US disclosed
US-4146631-A ANTIALLERGENS, RESPIRATORY DISORDERS MAY & BAKER LIMITED (GB) 1979-03-27 US disclosed
US-4024160-A Substituted 2-amino chromones and process for the preparation thereof WARNER-LAMBERT COMPANY (US) 1977-05-17 US disclosed
US-3932466-A Substituted 2-amino chromones and process for the preparation thereof WARNER-LAMBERT COMPANY (US) 1976-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260101914-A1 VANILLA COMPOSITION TAS2R19, TAS2R9, TAS2R39 CA12 2475/4885CA1 4358/4885CA2 3232/4885
US-20250377364-A1 REAGENT, METHOD, AND DEVICE FOR DETECTING ALBUMIN ALB, TTR, MTTP CA12 367/4885CA1 1488/4885CA2 3341/4885
US-12576055-B2 Disease detection and treatment based on trimethyl-lysine levels BHMT, BHMT2, EHMT2 CA12 1832/4885CA1 2402/4885CA2 1446/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.