SCHEMBL21243331

SCHEMBL21243331

CC1CCC(C(=O)OCC2CCCCC2)C(C(=O)OCC2CCCCC2)C1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.46
CYP3A4 P08684 1/20 0.46
LMNA P02545 1/20 0.45
TRPM8 Q7Z2W7 1/20 0.35
CHRM2 P08172 1/20 0.35
CHRM4 P08173 1/20 0.35
CHRM5 P08912 1/20 0.35
CHRM1 P11229 1/20 0.35
CHRM3 P20309 1/20 0.35
SLC1A3 P43003 3/20 0.35
SLC1A2 P43004 3/20 0.35
SLC1A1 P43005 3/20 0.35
EPHX1 P07099 4/20 0.34
GRM2 Q14416 1/20 0.33
GRM3 Q14832 1/20 0.33
PARP15 Q460N3 1/20 0.33
PARP10 Q53GL7 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21243329 0.89 TP53 (0.41) TP53CYP3A4LMNATRPM8EPHX1
SCHEMBL21243361 0.86 TP53 (0.53) TP53CYP3A4LMNACHRM2CHRM4
SCHEMBL11282546 0.86 LMNA (0.47) TP53CYP3A4LMNACHRM2CHRM4
SCHEMBL21243359 0.85 TP53 (0.60) TP53CYP3A4LMNACHRM2CHRM4
SCHEMBL21243358 0.85 TRPM8 (0.38) TP53CYP3A4LMNATRPM8EPHX1
SCHEMBL21243372 0.83 CHRM2 (0.39) TP53CYP3A4CHRM2CHRM4CHRM5
SCHEMBL21243382 0.82 TRPM8 (0.36) TP53CYP3A4LMNATRPM8EPHX1
SCHEMBL21243375 0.81 TRPM8 (0.41) TP53CYP3A4LMNATRPM8EPHX1
SCHEMBL21243337 0.81 LIPA (0.39) TP53CYP3A4TRPM8EPHX1
SCHEMBL14428796 0.81 CYP3A4 (0.51) TP53CYP3A4LMNACHRM2CHRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10947472-B2 Lubricant base oil for power transmission NEW JAPAN CHEMICAL CO., LTD. (JP) 2021-03-16 US disclosed
US-20190249103-A1 LUBRICANT BASE OIL FOR POWER TRANSMISSION NEW JAPAN CHEMICAL CO., LTD. (JP) 2019-08-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10947472-B2 Lubricant base oil for power transmission DNAH12, DYNC1LI1, DYNC1LI2 TP53 4733/4885CYP3A4 4194/4885LMNA 2553/4885
US-20190249103-A1 LUBRICANT BASE OIL FOR POWER TRANSMISSION DNAH12, DYNC1LI1, DYNC1LI2 TP53 4733/4885CYP3A4 4194/4885LMNA 2553/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.