SCHEMBL21243382

SCHEMBL21243382

CCCC1CCC(COC(=O)C2CCC(C)CC2C(=O)OCC2CCC(CCC)CC2)CC1

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TRPM8 Q7Z2W7 1/20 0.36
TP53 P04637 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C9 P11712 1/20 0.33
TLR4 O00206 1/20 0.32
ALDH1A1 P00352 2/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
EPHX1 P07099 1/20 0.32
KMT2A Q03164 1/20 0.31
PTGIR P43119 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21243369 0.91 HTT (0.39) TRPM8TP53CYP3A4CYP2C9TLR4
SCHEMBL21243329 0.89 TP53 (0.41) TRPM8TP53CYP3A4LMNAEPHX1
SCHEMBL21243358 0.87 TRPM8 (0.38) TRPM8TP53CYP3A4LMNAEPHX1
SCHEMBL21243365 0.85 TP53 (0.50) TP53CYP3A4CYP2C9ALDH1A1LMNA
SCHEMBL21243337 0.83 LIPA (0.39) TRPM8TP53CYP3A4ALDH1A1MAPT
SCHEMBL21243331 0.82 TP53 (0.46) TRPM8TP53CYP3A4LMNAEPHX1
SCHEMBL21243375 0.80 TRPM8 (0.41) TRPM8TP53CYP3A4LMNAEPHX1
SCHEMBL21243349 0.79 TP53 (0.37) TRPM8TP53CYP3A4EPHX1
SCHEMBL21243361 0.78 TP53 (0.53) TP53CYP3A4LMNAEPHX1PTGIR
SCHEMBL21243373 0.78 TLR4 (0.39) CYP2C9TLR4ALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10947472-B2 Lubricant base oil for power transmission NEW JAPAN CHEMICAL CO., LTD. (JP) 2021-03-16 US disclosed
US-20190249103-A1 LUBRICANT BASE OIL FOR POWER TRANSMISSION NEW JAPAN CHEMICAL CO., LTD. (JP) 2019-08-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10947472-B2 Lubricant base oil for power transmission DNAH12, DYNC1LI1, DYNC1LI2 TRPM8 1532/4885TP53 4733/4885CYP3A4 4194/4885
US-20190249103-A1 LUBRICANT BASE OIL FOR POWER TRANSMISSION DNAH12, DYNC1LI1, DYNC1LI2 TRPM8 1532/4885TP53 4733/4885CYP3A4 4194/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.