SCHEMBL21243343

SCHEMBL21243343

CC1CC(C)C(CCOC(=O)C2CCC(C)CC2C(=O)OCCC2C(C)CC(C)CC2C)C(C)C1

nearest known ligand 0.37

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TRPM8 Q7Z2W7 1/20 0.34
EPHX1 P07099 1/20 0.33
TP53 P04637 1/20 0.30
CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21243370 0.83 TP53 (0.39) TRPM8EPHX1TP53CYP3A4
SCHEMBL1196205 0.78 PPM1B (0.44) TRPM8EPHX1TP53CYP3A4
SCHEMBL28513099 0.78 TRPM8 (0.38) TRPM8EPHX1TP53CYP3A4
SCHEMBL21243372 0.77 CHRM2 (0.39) EPHX1TP53CYP3A4
SCHEMBL1196090 0.75 ALDH1A1 (0.44) TRPM8EPHX1
SCHEMBL21243340 0.73 TP53 (0.50) EPHX1TP53CYP3A4
SCHEMBL5524622 0.73 NAAA (0.43) TRPM8EPHX1
SCHEMBL21243362 0.73 TP53 (0.39) TRPM8EPHX1TP53CYP3A4
SCHEMBL18828251 0.73 TRPM8 (0.50) TRPM8EPHX1
SCHEMBL20073034 0.73 TRPM8 (0.50) TRPM8EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10947472-B2 Lubricant base oil for power transmission NEW JAPAN CHEMICAL CO., LTD. (JP) 2021-03-16 US disclosed
US-20190249103-A1 LUBRICANT BASE OIL FOR POWER TRANSMISSION NEW JAPAN CHEMICAL CO., LTD. (JP) 2019-08-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10947472-B2 Lubricant base oil for power transmission DNAH12, DYNC1LI1, DYNC1LI2 TRPM8 1532/4885EPHX1 1801/4885TP53 4733/4885
US-20190249103-A1 LUBRICANT BASE OIL FOR POWER TRANSMISSION DNAH12, DYNC1LI1, DYNC1LI2 TRPM8 1532/4885EPHX1 1801/4885TP53 4733/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.