Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENTPD1 | P49961 | 3/20 | 0.41 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | NT5E | P21589 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18531148 | 0.94 | ENTPD1 (0.41) | ENTPD1HSPA5ADORA3 | |
| SCHEMBL14948817 | 0.89 | HSPA5 (0.42) | ENTPD1HSPA5ADORA3 | |
| SCHEMBL18950207 | 0.86 | HSPA5 (0.43) | ENTPD1HSPA5ADORA3 | |
| SCHEMBL18852628 | 0.82 | ADK (0.43) | HSPA5ADORA3 | |
| SCHEMBL15746955 | 0.80 | HSPA5 (0.45) | HSPA5ADORA3 | |
| SCHEMBL17472296 | 0.79 | HSPA8 (0.45) | HSPA5ADORA3 | |
| SCHEMBL19007434 | 0.76 | HSPA5 (0.46) | HSPA5ADORA3 | |
| SCHEMBL22315144 | 0.73 | ADORA3 (0.51) | ENTPD1HSPA5ADORA3 | |
| SCHEMBL18464494 | 0.72 | ADK (0.51) | HSPA5ADORA3 | |
| SCHEMBL12369365 | 0.69 | ATG7 (0.36) | ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3520821-A1 | MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF BIOLOGICS AND PROTEINS ASSOCIATED WITH HUMAN DISEASE | Moderna Therapeutics, Inc. (US) | 2019-08-07 | — | — | EP | disclosed |