Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CDK4 | P11802 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CCND1 | P24385 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 3/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | DRD2 | P14416 | 3/20 | 0.39 |
| ▸ | DRD3 | P35462 | 3/20 | 0.39 |
| ▸ | SLC22A2 | O15244 | 2/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.39 |
| ▸ | SLC22A3 | O75751 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1198917 | 0.79 | ALDH1A1 (0.36) | MEN1KMT2AALDH1A1USP2CDK4 | |
| SCHEMBL1450910 | 0.79 | MEN1 (0.45) | MEN1KMT2AALDH1A1USP2CDK4 | |
| SCHEMBL23084321 | 0.76 | L3MBTL1 (0.38) | MEN1KMT2AALDH1A1USP2CDK4 | |
| SCHEMBL2604390 | 0.69 | MAOA (0.52) | MEN1KMT2AALDH1A1USP2CDK4 | |
| SCHEMBL22505286 | 0.67 | MAOA (0.42) | MEN1KMT2AALDH1A1USP2LMNA | |
| SCHEMBL862128 | 0.67 | TSHR (0.56) | DRD2DRD3HTR2CDRD1DRD4 | |
| SCHEMBL862127 | 0.67 | TSHR (0.56) | DRD2DRD3HTR2CDRD1DRD4 | |
| SCHEMBL827824 | 0.66 | ALDH1A1 (0.39) | MEN1KMT2AALDH1A1USP2CDK4 | |
| SCHEMBL142091 | 0.66 | ALDH1A1 (0.59) | MEN1KMT2AALDH1A1USP2CDK4 | |
| SCHEMBL10128232 | 0.66 | ALDH1A1 (0.52) | MEN1KMT2AALDH1A1USP2CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019153007-A2 | NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE INHIBITORS AND METHODS FOR USE OF THE SAME | THE BOARO OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2019-08-08 | — | — | WO | disclosed |