SCHEMBL1198917

SCHEMBL1198917

CN1C=CCc2ccccc21

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.36
MEN1 O00255 5/20 0.36
KMT2A Q03164 5/20 0.36
SMN1; SMN2 Q16637 4/20 0.36
USP2 O75604 2/20 0.36
HPGD P15428 2/20 0.36
CDK4 P11802 1/20 0.36
ALOX15 P16050 1/20 0.36
CCND1 P24385 1/20 0.36
HTR2A P28223 6/20 0.36
DRD2 P14416 4/20 0.34
DRD3 P35462 4/20 0.34
DRD1 P21728 3/20 0.34
DRD4 P21917 3/20 0.34
MAOA P21397 2/20 0.34
MAOB P27338 2/20 0.34
DRD5 P21918 2/20 0.34
ADRA2C P18825 5/20 0.34
LMNA P02545 5/20 0.33
SLC6A2 P23975 5/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21245929 0.79 MEN1 (0.42) ALDH1A1MEN1KMT2ASMN1; SMN2USP2
SCHEMBL14225122 0.79 KDM4E (0.31) ALDH1A1MEN1KMT2ASMN1; SMN2HPGD
SCHEMBL827824 0.77 ALDH1A1 (0.39) ALDH1A1MEN1KMT2ASMN1; SMN2USP2
SCHEMBL374979 0.76 ALDH1A1 (0.33) ALDH1A1MEN1KMT2ASMN1; SMN2USP2
SCHEMBL9008263 0.75 ALDH1A1 (0.42) ALDH1A1MEN1KMT2AUSP2CDK4
SCHEMBL1375450 0.74 NPC1 (0.35) ALDH1A1MEN1KMT2ASMN1; SMN2USP2
SCHEMBL4838387 0.74 HTR2A (0.36) ALDH1A1MEN1KMT2ASMN1; SMN2USP2
SCHEMBL553792 0.74 NPC1 (0.35) ALDH1A1MEN1KMT2ASMN1; SMN2USP2
SCHEMBL2073990 0.74 HTR2A (0.36) ALDH1A1MEN1KMT2ASMN1; SMN2USP2
SCHEMBL15010759 0.74 POLB (0.33) ALDH1A1MEN1KMT2ASMN1; SMN2USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 268 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12559453-B2 Sulfonic acid-modified polyisocyanate and preparation method therefor WANHUA CHEMICAL GROUP CO., LTD. (CN) 2026-02-24 US claimed
EP-4144780-B1 SULFONIC ACID-MODIFIED POLYISOCYANATE AND PREPARATION METHOD THEREFOR WANHUA CHEMICAL GROUP CO LTD (CN) 2025-12-24 EP claimed
CN-119751530-A Boron drug with tumor targeted release capability for boron neutron capture treatment and preparation method thereof 南通大学附属医院 2025-04-04 CN claimed
CN-118184643-A DNA embedded fluorescence quenching compound and preparation method and application thereof 广东普洛凯生物科技有限公司 2024-06-14 CN claimed
CN-115466201-B Sulfonic acid modified polyisocyanate and preparation method thereof 万华化学集团股份有限公司 2024-05-03 CN claimed
CN-117263928-A Fluorescent probe and preparation method thereof 南通大学 2023-12-22 CN claimed
CN-117263858-A Double-quinoline NADH fluorescent probe and preparation method thereof 南通大学 2023-12-22 CN claimed
CN-115228437-B Surface modification method for making active carbon surface positive 四川轻化工大学 2023-10-31 CN claimed
US-20230257344-A1 SULFONIC ACID-MODIFIED POLYISOCYANATE AND PREPARATION METHOD THEREFOR WANHUA CHEMICAL GROUP CO., LTD. (CN) 2023-08-17 US claimed
CN-115632148-B Hybrid power generation system and method 北京海望氢能科技有限公司 2023-03-21 CN claimed
EP-4144780-A1 SULFONIC ACID-MODIFIED POLYISOCYANATE AND PREPARATION METHOD THEREFOR Wanhua Chemical Group Co., Ltd. (CN) 2023-03-08 EP claimed
WO-2022257585-A1 SULFONIC ACID-MODIFIED POLYISOCYANATE AND PREPARATION METHOD THEREFOR 万华化学集团股份有限公司 2022-12-15 WO claimed
CN-115466201-A Sulfonic acid modified polyisocyanate and preparation method thereof 万华化学集团股份有限公司 2022-12-13 CN claimed
CN-107324975-A Direct hydroxylation or amination method of photocatalytic benzene and derivatives thereof 中国科学院理化技术研究所 2017-11-07 CN claimed
CN-103724623-B A kind of preparation method of solvable meltability copolyimide moulding compound 上海市合成树脂研究所 2016-06-29 CN claimed
EP-0736111-B1 METALLIC SCREEN MATERIAL HAVING A STRAND OR FIBRE STRUCTURE, AND METHOD FOR MANUFACTURING SUCH A MATERIAL STORK SCREENS BV (NL) 1999-04-21 EP claimed
US-4894409-A BLEND OR AMINO GROUP CONTAINING DIENE POLYMER AND SILICA FILLER NONCRACKING, WEAR RESISTANCE JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1990-01-16 US claimed
JP-61251665-A None JP disclosed
EP-0106175-A2 Electrically conductive liquid crystalline substance and polymer SHOWA DENKO KABUSHIKI KAISHA (JP) 1984-04-25 EP disclosed
US-4346015-A Method of improving antiwear properties of high temperature hydrocarbon compositions UNION CARBIDE CORPORATION (US) 1982-08-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230257344-A1 SULFONIC ACID-MODIFIED POLYISOCYANATE AND PREPARATION METHOD THEREFOR TST, SULT1A1, SULT2A1 ALDH1A1 1641/4885MEN1 3118/4885KMT2A 1204/4885
US-12559453-B2 Sulfonic acid-modified polyisocyanate and preparation method therefor TMT1A, SRMS, FTO ALDH1A1 744/4885MEN1 3395/4885KMT2A 368/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.